doi: 10.1038/304699a0.
Priming for and induction of anti-poliovirus neutralizing antibodies by synthetic peptides
- PMID: 6310403
- DOI: 10.1038/304699a0
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Priming for and induction of anti-poliovirus neutralizing antibodies by synthetic peptides
Nature.
1983 Aug.
Abstract
Five peptides containing amino acid sequences from the type 1 poliovirus structural protein VP1 have been synthesized. Each of the peptides was found capable of priming the immune system of rabbits for a long-lasting, virus-neutralizing IgG antibody response following a single inoculation of intact virus. One peptide directly induced the production of neutralizing antibody.
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