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. 1980 Jul;77(7):3865-9.
doi: 10.1073/pnas.77.7.3865.

Deletions covering the putative promoter region of early mRNAs of simian virus 40 do not abolish T-antigen expression

C Benoist, P Chambon

Deletions covering the putative promoter region of early mRNAs of simian virus 40 do not abolish T-antigen expression

C Benoist et al. Proc Natl Acad Sci U S A. 1980 Jul.

Abstract

A recombinant plasmid was constructed by insertion of the early genes of simian virus 40 (SV40) into pBR322. When it was introduced into eukaryotic cells, the SV40 early genes were expressed. We have made deletion mutants of this plasmid, from which the major cap sites of SV40 early mRNAs have been removed along with some of the sequences upstream. The deleted sequences appear to be dispensable for early gene expression, but this does not necessarily imply that they serve no function in the initiation of transcription on wild-type SV40.

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References

    1. J Natl Cancer Inst. 1968 Aug;41(2):351-7 - PubMed
    1. Virology. 1973 Apr;52(2):456-67 - PubMed
    1. Eur J Biochem. 1974 Jan 16;41(2):367-78 - PubMed
    1. Virology. 1974 Nov;62(1):112-24 - PubMed
    1. Proc Natl Acad Sci U S A. 1976 Sep;73(9):3083-7 - PubMed

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