Structure of the catalytic and antigenic sites in influenza virus neuraminidase
- PMID: 6188957
- DOI: 10.1038/303041a0
Structure of the catalytic and antigenic sites in influenza virus neuraminidase
Abstract
The catalytic sites of influenza virus neuraminidase are located on the upper corners of the box-shaped tetramer that forms the head of the molecule. Antigenic determinants form a nearly-continuous surface across the top of the monomer encircling the catalytic site. Approximately the same number of amino acid sequence changes occurred in these determinants between the years 1968 and 1975 as occurred in the antigenic sites of influenza virus haemagglutinin in the same period.
Similar articles
-
The neuraminidase of influenza virus.Proteins. 1989;6(4):341-56. doi: 10.1002/prot.340060402. Proteins. 1989. PMID: 2482974 Review.
-
Three-dimensional structure of a complex of antibody with influenza virus neuraminidase.Nature. 1987 Mar 26-Apr 1;326(6111):358-63. doi: 10.1038/326358a0. Nature. 1987. PMID: 2436051
-
Antibody recognition of the influenza virus neuraminidase.Cold Spring Harb Symp Quant Biol. 1989;54 Pt 1:247-55. doi: 10.1101/sqb.1989.054.01.031. Cold Spring Harb Symp Quant Biol. 1989. PMID: 2484161 Review. No abstract available.
-
[Serological study of the neuraminidase activity of cholera filtrate and influenza virus].Vopr Virusol. 1975 Jan-Feb;(1):34-9. Vopr Virusol. 1975. PMID: 1121851 Russian.
-
[Antigenic characteristics of chicken influenza viruses].Vopr Virusol. 1976 May-Jun;(3):318-21. Vopr Virusol. 1976. PMID: 62456 Russian.
Cited by
-
Antiviral adhesion molecular mechanisms for influenza: W. G. Laver's lifetime obsession.Philos Trans R Soc Lond B Biol Sci. 2015 Feb 5;370(1661):20140034. doi: 10.1098/rstb.2014.0034. Philos Trans R Soc Lond B Biol Sci. 2015. PMID: 25533092 Free PMC article. Review.
-
Prior infection of pigs with a recent human H3N2 influenza virus confers minimal cross-protection against a European swine H3N2 virus.Influenza Other Respir Viruses. 2013 Nov;7(6):1260-8. doi: 10.1111/irv.12105. Epub 2013 Mar 29. Influenza Other Respir Viruses. 2013. PMID: 23551882 Free PMC article.
-
In silico analysis of drug-resistant mutant of neuraminidase (N294S) against oseltamivir.Protoplasma. 2013 Feb;250(1):197-207. doi: 10.1007/s00709-012-0394-6. Epub 2012 Mar 6. Protoplasma. 2013. PMID: 22392098
-
Fatal cases of influenza A(H3N2) in children: insights from whole genome sequence analysis.PLoS One. 2012;7(3):e33166. doi: 10.1371/journal.pone.0033166. Epub 2012 Mar 6. PLoS One. 2012. PMID: 22412998 Free PMC article.
-
Conserved sequences in bacterial and viral sialidases.Glycoconj J. 1989;6(3):349-53. doi: 10.1007/BF01047853. Glycoconj J. 1989. PMID: 2562507
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Other Literature Sources