Regulation of nitrogen metabolism in glutamine auxotrophs of Klebsiella pneumoniae
- PMID: 6102985
- PMCID: PMC293910
- DOI: 10.1128/jb.142.1.99-110.1980
Regulation of nitrogen metabolism in glutamine auxotrophs of Klebsiella pneumoniae
Abstract
We examined the regulation of nitrogen metabolism in four classes (glnA, glnB, glnF, and glnG) of Gln- auxotrophs of Klebsiella pneumoniae. These studies indicate that glutamine synthetase does not directly mediate the physiological response to NH4+ in this organism. We present evidence suggesting that the effect of NH4+ on the expression of genes involved in nitrogen metabolism involves the products of the glnF and glnG genes.
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