Mortality rates of persons entering methadone maintenance: a seven-year study
- PMID: 539576
- DOI: 10.3109/00952997909001723
Mortality rates of persons entering methadone maintenance: a seven-year study
Abstract
An analysis of all deaths occurring over a 79-month period in patients enrolled in methadone maintenance (MM) revealed an overall mortality rate of 20/1,000. Over a similar period 510 persons were discharged from MM. Follow-up able to be performed in 80% revealed at least 22 deaths to have occurred subsequent to discharge. Survival curves calculated on the basis of these data indicate that even under the best possible assumption, age adjusted mortality rates of heroin addicts are not only above the national mean but are one and a half times that of the population in the community surrounding the clinic. None of the deaths could be directly attributed to methadone. Alcohol was prominent in 60% of all deaths, being responsible for 89% of medical deaths and present in 35% of violent deaths. These findings emphasize the persistent risk associated with heroin addiction as well as the role of alcoholism in the production of excessive mortality.
Similar articles
-
A 25-year follow-up of patients admitted to methadone treatment for the first time: mortality and gender differences.Addict Behav. 2011 Dec;36(12):1184-90. doi: 10.1016/j.addbeh.2011.07.019. Epub 2011 Jul 22. Addict Behav. 2011. PMID: 21835551
-
Association between availability of heroin and methadone and fatal poisoning in England and Wales 1993-2004.Int J Epidemiol. 2006 Dec;35(6):1579-85. doi: 10.1093/ije/dyl207. Epub 2006 Oct 30. Int J Epidemiol. 2006. PMID: 17077102
-
Benefits of retention in methadone maintenance and chronic medical conditions as risk factors for premature death among older heroin addicts.J Psychiatr Pract. 2009 May;15(3):227-34. doi: 10.1097/01.pra.0000351884.83377.e2. J Psychiatr Pract. 2009. PMID: 19461397
-
[What effects does methadone maintenance treatment have on the rehabilitation of heroin addicts?].Tidsskr Nor Laegeforen. 1998 Aug 30;118(20):3139-41. Tidsskr Nor Laegeforen. 1998. PMID: 9760857 Review. Norwegian.
-
Methadone maintenance treatment (MMT): a review of historical and clinical issues.Mt Sinai J Med. 2000 Oct-Nov;67(5-6):347-64. Mt Sinai J Med. 2000. PMID: 11064485 Review.
Cited by
-
Hepatic cirrhosis in young adults: association with adolescent onset of alcohol and parenteral heroin abuse.Gut. 1985 Jan;26(1):8-13. doi: 10.1136/gut.26.1.8. Gut. 1985. PMID: 3855296 Free PMC article.
-
Pharmacotherapy of dual substance abuse and dependence.CNS Drugs. 2007;21(3):213-37. doi: 10.2165/00023210-200721030-00003. CNS Drugs. 2007. PMID: 17338593 Review.
-
Pharmacogenetics of Opioid Use Disorder Treatment.CNS Drugs. 2018 Apr;32(4):305-320. doi: 10.1007/s40263-018-0513-9. CNS Drugs. 2018. PMID: 29623639 Free PMC article. Review.
-
Addict death rates during a four-year posttreatment follow-up.Am J Public Health. 1982 Jul;72(7):703-9. doi: 10.2105/ajph.72.7.703. Am J Public Health. 1982. PMID: 7091460 Free PMC article.
-
Mortality among injection drug users identified as "out of treatment".Am J Public Health. 1995 Jan;85(1):119-20. doi: 10.2105/ajph.85.1.119. Am J Public Health. 1995. PMID: 7832249 Free PMC article. No abstract available.
MeSH terms
Substances
LinkOut - more resources
Full Text Sources