doi: 10.1126/science.181.4100.665.
Murine C-type RNA virus from spontaneous neoplasms: in vitro host range and oncogenic potential
- PMID: 4353359
- DOI: 10.1126/science.181.4100.665
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Murine C-type RNA virus from spontaneous neoplasms: in vitro host range and oncogenic potential
Science.
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Abstract
Strain BALB/c mice harbor at least two host range variants of marine leukemia virus. One variant, which is host-cell tropic, is the predominant isolate from neoplastic tissues and produced lymphoreticular neoplasms when injected into BALB/c newborn mice. A second variant, whicht is isolated throughout life, grows poorly in host embryonic cells in culture and was not associated with lymphoreticular neoplasm induction when injected into newborn BALB/c mice.
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