Comparative Study
doi: 10.1128/jcm.22.6.1071-1072.1985.
Comparison of ortho respiratory syncytial virus enzyme-linked immunosorbent assay and HEp-2 cell culture
- PMID: 4066920
- PMCID: PMC271886
- DOI: 10.1128/jcm.22.6.1071-1072.1985
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Comparative Study
Comparison of ortho respiratory syncytial virus enzyme-linked immunosorbent assay and HEp-2 cell culture
J Clin Microbiol.
1985 Dec.
Abstract
Two hundred seventy nasopharyngeal aspirates were tested in duplicate with the Ortho Diagnostics, Inc. (Raritan, N.J.), respiratory syncytial virus antigen enzyme-linked immunosorbent assay. The test was sensitive (80 to 82%) and specific (96%) when compared with cell culture. The enzyme-linked immunosorbent assay detected seven antigen-positive specimens not among the 71 specimens that were positive for respiratory syncytial virus in cell culture. A blocking test confirmed those specimens as true positives (specificity, 100%).
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