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Review
. 2024 Feb 10;44(1):53.
doi: 10.1007/s10792-024-03049-1.

The application of high-throughput sequencing technology in corneal diseases

Jing Yi Zhao #  1 , Yu Xi He #  2 , Mei Liang Wu  2 , Rui Qing Wang  3
Affiliations
Review

The application of high-throughput sequencing technology in corneal diseases

Jing Yi Zhao et al. Int Ophthalmol. .

Abstract

High-throughput sequencing technology, also known as next-generation sequencing technology, can explore new biomarkers and specific gene mutations. It has a pivotal role in promoting the gene research, which can limit the detection area, lessen the time needed for sequencing. Also, it can quickly screen out the suspected pathogenic genes of patients, gain the necessary genetic data, and provide the basis for clinical diagnosis and genetic counseling. In the research of corneal diseases, through the DNA sequencing of patients' diseased cells, it can provide a deeper understanding of corneal diseases and improve the diagnosis, classification and treatment alternatives of various corneal diseases. This article will introduce the application progress of high-throughput sequencing technology in corneal diseases, which will help to understand the application of this technology in various corneal diseases.

Keywords: Adjuvant therapy; Corneal diseases; Disease diagnosis; High-throughput sequencing.

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Conflict of interest statement

The authors declare that they have no competing interests in this section.

Figures

Fig. 1
Fig. 1
The process of high-throughput sequencing technology (by Figdraw)
See this image and copyright information in PMC

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