The Blood-Brain Barrier in Health and Disease

doi:10.3390/ijms24119261

Editorial

. 2023 May 25;24(11):9261.

doi: 10.3390/ijms24119261.

The Blood-Brain Barrier in Health and Disease

Sweilem B Al Rihani¹, Yazan S Batarseh², Amal Kaddoumi³

Affiliations

¹ Tabula Rasa HealthCare, Precision Pharmacotherapy Research and Development Institute, Orlando, FL 32827, USA.
² Department of Pharmacology and Biomedical Sciences, Faculty of Pharmacy and Medical Sciences, University of Petra, Amman 1196, Jordan.
³ Department of Drug Discovery and Development, Harrison College of Pharmacy, Auburn University, 720 S Donahue Drive, Auburn, AL 36849, USA.

PMID: 37298209
PMCID: PMC10252347
DOI: 10.3390/ijms24119261

Editorial

The Blood-Brain Barrier in Health and Disease

Sweilem B Al Rihani et al. Int J Mol Sci. 2023.

. 2023 May 25;24(11):9261.

doi: 10.3390/ijms24119261.

Authors

Sweilem B Al Rihani¹, Yazan S Batarseh², Amal Kaddoumi³

Affiliations

¹ Tabula Rasa HealthCare, Precision Pharmacotherapy Research and Development Institute, Orlando, FL 32827, USA.
² Department of Pharmacology and Biomedical Sciences, Faculty of Pharmacy and Medical Sciences, University of Petra, Amman 1196, Jordan.
³ Department of Drug Discovery and Development, Harrison College of Pharmacy, Auburn University, 720 S Donahue Drive, Auburn, AL 36849, USA.

PMID: 37298209
PMCID: PMC10252347
DOI: 10.3390/ijms24119261

Abstract

The blood-brain barrier (BBB) is a complex network of tightly regulated cells and transport proteins that separate the circulating blood from the brain tissue [...].

PubMed Disclaimer

Conflict of interest statement

The authors declare no conflict of interest.

Cited by

Protection of Tight Junctional Complexes between hCMEC/D3 Cells by Deep-Sea Fibrinolytic Compound FGFC1.
Diao X, Han H, Sun H, Zhang H, Wu W. Diao X, et al. Mar Drugs. 2024 Jul 26;22(8):341. doi: 10.3390/md22080341. Mar Drugs. 2024. PMID: 39195457 Free PMC article.

References

1. Kadry H., Noorani B., Cucullo L. A blood-brain barrier overview on structure, function, impairment, and biomarkers of integrity. Fluids Barriers CNS. 2020;17:69. doi: 10.1186/s12987-020-00230-3. - DOI - PMC - PubMed
1. Persidsky Y., Ramirez S.H., Haorah J., Kanmogne G.D. Blood-brain barrier: Structural components and function under physiologic and pathologic conditions. J. Neuroimmune Pharm. 2006;1:223–236. doi: 10.1007/s11481-006-9025-3. - DOI - PubMed
1. Harilal S., Jose J., Parambi D.G.T., Kumar R., Unnikrishnan M.K., Uddin M.S., Mathew G.E., Pratap R., Marathakam A., Mathew B. Revisiting the blood-brain barrier: A hard nut to crack in the transportation of drug molecules. Brain Res. Bull. 2020;160:121–140. doi: 10.1016/j.brainresbull.2020.03.018. - DOI - PubMed
1. Erickson M.A., Rhea E.M., Knopp R.C., Banks W.A. Interactions of SARS-CoV-2 with the Blood–Brain Barrier. Int. J. Mol. Sci. 2021;22:2681. doi: 10.3390/ijms22052681. - DOI - PMC - PubMed
1. Al Rihani S.B., Darakjian L.I., Deodhar M., Dow P., Turgeon J., Michaud V. Disease-Induced Modulation of Drug Transporters at the Blood–Brain Barrier Level. Int. J. Mol. Sci. 2021;22:3742. doi: 10.3390/ijms22073742. - DOI - PMC - PubMed

Publication types

Actions

MeSH terms

Actions
Actions
Actions
Actions

Substances

Actions

LinkOut - more resources

Full Text Sources

[1] Kadry H., Noorani B., Cucullo L. A blood-brain barrier overview on structure, function, impairment, and biomarkers of integrity. Fluids Barriers CNS. 2020;17:69. doi: 10.1186/s12987-020-00230-3. - DOI - PMC - PubMed

[2] Kadry H., Noorani B., Cucullo L. A blood-brain barrier overview on structure, function, impairment, and biomarkers of integrity. Fluids Barriers CNS. 2020;17:69. doi: 10.1186/s12987-020-00230-3. - DOI - PMC - PubMed

[3] Persidsky Y., Ramirez S.H., Haorah J., Kanmogne G.D. Blood-brain barrier: Structural components and function under physiologic and pathologic conditions. J. Neuroimmune Pharm. 2006;1:223–236. doi: 10.1007/s11481-006-9025-3. - DOI - PubMed

[4] Persidsky Y., Ramirez S.H., Haorah J., Kanmogne G.D. Blood-brain barrier: Structural components and function under physiologic and pathologic conditions. J. Neuroimmune Pharm. 2006;1:223–236. doi: 10.1007/s11481-006-9025-3. - DOI - PubMed

[5] Harilal S., Jose J., Parambi D.G.T., Kumar R., Unnikrishnan M.K., Uddin M.S., Mathew G.E., Pratap R., Marathakam A., Mathew B. Revisiting the blood-brain barrier: A hard nut to crack in the transportation of drug molecules. Brain Res. Bull. 2020;160:121–140. doi: 10.1016/j.brainresbull.2020.03.018. - DOI - PubMed

[6] Harilal S., Jose J., Parambi D.G.T., Kumar R., Unnikrishnan M.K., Uddin M.S., Mathew G.E., Pratap R., Marathakam A., Mathew B. Revisiting the blood-brain barrier: A hard nut to crack in the transportation of drug molecules. Brain Res. Bull. 2020;160:121–140. doi: 10.1016/j.brainresbull.2020.03.018. - DOI - PubMed

[7] Erickson M.A., Rhea E.M., Knopp R.C., Banks W.A. Interactions of SARS-CoV-2 with the Blood–Brain Barrier. Int. J. Mol. Sci. 2021;22:2681. doi: 10.3390/ijms22052681. - DOI - PMC - PubMed

[8] Erickson M.A., Rhea E.M., Knopp R.C., Banks W.A. Interactions of SARS-CoV-2 with the Blood–Brain Barrier. Int. J. Mol. Sci. 2021;22:2681. doi: 10.3390/ijms22052681. - DOI - PMC - PubMed

[9] Al Rihani S.B., Darakjian L.I., Deodhar M., Dow P., Turgeon J., Michaud V. Disease-Induced Modulation of Drug Transporters at the Blood–Brain Barrier Level. Int. J. Mol. Sci. 2021;22:3742. doi: 10.3390/ijms22073742. - DOI - PMC - PubMed

[10] Al Rihani S.B., Darakjian L.I., Deodhar M., Dow P., Turgeon J., Michaud V. Disease-Induced Modulation of Drug Transporters at the Blood–Brain Barrier Level. Int. J. Mol. Sci. 2021;22:3742. doi: 10.3390/ijms22073742. - DOI - PMC - PubMed

Save citation to file

Email citation

Add to Collections

Add to My Bibliography

Your saved search

Create a file for external citation management software

Your RSS Feed

The Blood-Brain Barrier in Health and Disease

Affiliations

The Blood-Brain Barrier in Health and Disease

Authors

Affiliations

Abstract

Conflict of interest statement

Similar articles

Cited by

References

Publication types

MeSH terms

Substances

LinkOut - more resources

Full Text Sources

Abstract

Conflict of interest statement

Similar articles

Cited by

References

Publication types

MeSH terms

Substances

Related information

LinkOut - more resources

Full Text Sources