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Review
. 2023 May 15;14(5):565-572.
doi: 10.4239/wjd.v14.i5.565.

Exercise therapy for sarcopenia and diabetes

Seung-Taek Lim  1   2 , Sunghwun Kang  3   4
Affiliations
Review

Exercise therapy for sarcopenia and diabetes

Seung-Taek Lim et al. World J Diabetes. .

Abstract

Aging is characterized by the gradual deterioration of function at the molecular, cellular, tissue, and organism levels in humans. The typical diseases caused by changes in body composition, as well as functional decline in the human body's organs due to aging include sarcopenia and metabolic disorders. The accumulation of dysfunctional aging β cells with age can cause decreased glucose tolerance and diabetes. Muscle decline has a multifactorial origin, involving lifestyle habits, disease triggers, and age-dependent biological changes. The reduced function of β cells in elderly people lowers insulin sensitivity, which affects protein synthesis and interferes with muscle synthesis. The functional decrease and aggravation of disease in elderly people with less regular exercise or physical activity causes imbalances in food intake and a continuous, vicious cycle. In contrast, resistance exercise increases the function of β cells and protein synthesis in elderly people. In this review, we discuss regular physical activities or exercises to prevent and improve health, which is sarcopenia as decreased muscle mass and metabolic disorders as diabetes in the elderly.

Keywords: Aging; Diabetes; Elderly; Muscle; Resistance exercise; Sarcopenia.

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Conflict of interest statement

Conflict-of-interest statement: The authors declare that they have no competing interests.

Figures

Figure 1
Figure 1
The summary of the factors that cause diabetes and sarcopenia due to the aging and benefits of resistance exercise in the elderly is as follows.
See this image and copyright information in PMC

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