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Clinical Trial
. 1987 Feb;80(2):91-3.
doi: 10.1177/014107688708000210.

Effectiveness of amantadine in reducing relapses in multiple sclerosis

Clinical Trial

Effectiveness of amantadine in reducing relapses in multiple sclerosis

G S Plaut. J R Soc Med. 1987 Feb.

Abstract

Fifty-three patients with multiple sclerosis were assessed in a double-blind multicentre study for the effect of amatadine. The patients were observed in general practices for up to four years. Relapses occurred in 5 of the 24 patients treated with amantadine and in 14 of the 29 placebo-treated patients. Neurological deterioration was not significantly different in the two groups.

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