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Review
. 1986;4(1):1-9.

Specific immunoglobulin M and G antibodies in the rapid diagnosis of human treponemal infections

  • PMID: 3514069
Review

Specific immunoglobulin M and G antibodies in the rapid diagnosis of human treponemal infections

F Müller. Diagn Immunol. 1986.

Abstract

The serological response to treponemal infections in men before and after specific treatment is analyzed. From the described observations several consequences and possibilities for a specific immunological diagnosis are discussed. In particular, it is shown that early diagnosis of syphilis in need of treatment can be achieved by demonstration of T pallidum-specific IgM antibodies. Finally, new insights into the role of antibody correlations between serum and cerebrospinal fluid are mentioned that have established the detection of asymptomatic neurosyphilis.

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