doi: 10.1038/273354a0.
A mutation affecting the sigma subunit of RNA polymerase changes transcriptional specificity
- PMID: 351406
- DOI: 10.1038/273354a0
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A mutation affecting the sigma subunit of RNA polymerase changes transcriptional specificity
Nature.
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Abstract
The RNA polymerase mutation, alt-1, affects the sigma subunit and alters the in vitro selectivity of RNA polymerase to parallel the in vivo phenotype. We propose that the mutation changes the distribution of functionally distinct polymerase isomers.
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