Expression of the c-myb proto-oncogene during cellular proliferation
- PMID: 3511387
- DOI: 10.1038/319374a0
Expression of the c-myb proto-oncogene during cellular proliferation
Abstract
In several cell types, messenger RNA levels of the nuclear proto-oncogene c-myb vary as a function of cellular proliferation; a transient increase in c-myb steady-state mRNA, mediated by post-transcriptional mechanisms, occurs during cell-cycle progression. In contrast, both quiescent and proliferating immature thymocytes contain exceptionally high levels of c-myb mRNA as a consequence of increased c-myb transcription.
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