doi: 10.1016/0198-8859(86)90069-8.
New class I in man: serological and molecular characterization
- PMID: 3488984
- DOI: 10.1016/0198-8859(86)90069-8
Item in Clipboard
New class I in man: serological and molecular characterization
Hum Immunol.
1986 Sep.
Abstract
New class I antigens in linkage disequilibrium with HLA-A antigen are demonstrated in PHA T and EBV preferential target cells using human alloantisera. These new antigens are defined as class I antigens by immunoprecipitation of a 41-12 k dimer. The molecule is shown to be distinct from the HLA-A, -B, -C molecule and in particular from the A3 molecule as in sequential immunoprecipitations, the depletion of the HLA-A, -B, -C molecule or A3 molecule (44-12 k) has no effect on the new molecule (41-12 k). Being present on the PHA T cells and lymphoblast lines, these antigens are considered as new epitopes involved in the the cell activation process.
Similar articles
-
[Demonstration of new class I antigens in man].Pathol Biol (Paris). 1987 Dec;35(10):1325-32. Pathol Biol (Paris). 1987. PMID: 2963994 French.
-
New human MHC class I antigens segregating with HLA-A antigens detected on some lymphocyte subpopulations.Hum Immunol. 1986 Feb;15(2):175-97. doi: 10.1016/0198-8859(86)90025-x. Hum Immunol. 1986. PMID: 3485086
-
Alloantisera with apparent HLA-A specificity reacting only against phytohemagglutinin-activated cells.Ric Clin Lab. 1986 Jul-Sep;16(3):449-56. doi: 10.1007/BF02886740. Ric Clin Lab. 1986. PMID: 2433726
-
Expression of MHC class II antigens in human B-cell leukaemia and non-Hodgkin's lymphoma.Br J Cancer. 1986 Feb;53(2):161-73. doi: 10.1038/bjc.1986.31. Br J Cancer. 1986. PMID: 3513812 Free PMC article. Review.
-
The T lymphoblastic malignancies.Cancer Chemother Pharmacol. 1980;4(1):11-5. doi: 10.1007/BF00255452. Cancer Chemother Pharmacol. 1980. PMID: 6988098 Review. No abstract available.
Cited by
-
Organization of the human class I major histocompatibility complex genes.Immunol Res. 1987;6(1-2):1-10. doi: 10.1007/BF02918100. Immunol Res. 1987. PMID: 3040873 Review. No abstract available.
-
Isolation of a human major histocompatibility complex class I gene encoding a nonubiquitous molecule expressed on activated lymphocytes.Proc Natl Acad Sci U S A. 1987 May;84(9):2872-6. doi: 10.1073/pnas.84.9.2872. Proc Natl Acad Sci U S A. 1987. PMID: 3033667 Free PMC article.
-
Transfer and expression of three cloned human non-HLA-A,B,C class I major histocompatibility complex genes in mutant lymphoblastoid cells.Proc Natl Acad Sci U S A. 1988 Jan;85(1):227-31. doi: 10.1073/pnas.85.1.227. Proc Natl Acad Sci U S A. 1988. PMID: 3257565 Free PMC article.
-
Activated human T lymphocytes express MHC class I heavy chains not associated with beta 2-microglobulin.J Exp Med. 1990 May 1;171(5):1431-42. doi: 10.1084/jem.171.5.1431. J Exp Med. 1990. PMID: 2139695 Free PMC article.
-
Molecular definition of a polymorphic antigen (LA45) of free HLA-A and -B heavy chains found on the surfaces of activated B and T cells.J Exp Med. 1991 Nov 1;174(5):1085-95. doi: 10.1084/jem.174.5.1085. J Exp Med. 1991. PMID: 1940790 Free PMC article.
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Research Materials
