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. 1987 Nov;84(21):7524-8.
doi: 10.1073/pnas.84.21.7524.

Spin glasses and the statistical mechanics of protein folding

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Spin glasses and the statistical mechanics of protein folding

J D Bryngelson et al. Proc Natl Acad Sci U S A. 1987 Nov.

Abstract

The theory of spin glasses was used to study a simple model of protein folding. The phase diagram of the model was calculated, and the results of dynamics calculations are briefly reported. The relation of these results to folding experiments, the relation of these hypotheses to previous protein folding theories, and the implication of these hypotheses for protein folding prediction schemes are discussed.

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