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. 2022 Oct;24(5):1122-1128.
doi: 10.1007/s10903-021-01263-y. Epub 2021 Aug 28.

Liver Cirrhosis, Etiology and Clinical Characteristics Disparities Among Minority Population

Muhammad Abu Tailakh  1   2 , Liat Poupko  3 , Najwan Kayyal  4 , Ali Alsana  4 , Asia Estis-Deaton  4 , Ohad Etzion  5   6 , Alexander Fich  5   6 , David Yardni  5   6 , Naim Abu-Freha  7   8
Affiliations

Liver Cirrhosis, Etiology and Clinical Characteristics Disparities Among Minority Population

Muhammad Abu Tailakh et al. J Immigr Minor Health. 2022 Oct.

Abstract

Liver cirrhosis (LC) is a common disease with varied primary causes and ethnic disparities. Clinical characteristics and outcomes of Arab Bedouin (AB) and Jewish patients with LC were retrospective collected and compared. We included 1048 patients, 95 (9%) Arab Bedouin and 953 (91%) Jewish patients. The incidence of cirrhosis was much lower among AB. Age at diagnosis was 47 ± 18 years among Bedouins compared to 61 ± 13 years (p < 0.001) among Jews. The most frequent causes of cirrhosis among Bedouin patients were fatty liver 21.1%, cryptogenic 20%, hepatitis B 17.9% and autoimmune hepatitis 15.8%, while hepatitis C (39.2%), fatty liver (17.2%) and alcoholic liver disease (14.4%) were most common among Jewish patients. An all-cause mortality of 48.4% was observed in AB patients compared to 66.4% in Jewish patients (p < 0.001). Significant disparities regarding incidence, clinical characteristics and outcomes of cirrhosis among Arab Bedouin compared with Jewish population were found.

Keywords: Arab Bedouin; Cirrhosis; Complications; Jews; Mortality.

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References

    1. Byass P. The global burden of liver disease: a challenge for methods and for public health. BMC Med. 2014;12:159. - DOI
    1. Jewell J, Sheron N. Trends in European liver death rates: implications for alcohol policy. Clin Med. 2010;10:259–63. - DOI
    1. Sepanlou SG, Malekzadeh F, Delavari F, et al. Burden of gastrointestinal and liver diseases in Middle East and North Africa: results of global burden of diseases study from 1990 to 2010. Middle East J Dig Dis. 2015;7(4):201–15. - PubMed - PMC
    1. Alazawi W, Cunningham M, Dearden J, Foster GR. Systematic review: outcome of compensated cirrhosis due to chronic hepatitis C infection. Aliment Pharmacol Ther. 2010;32(3):344–55. - DOI
    1. Kandeel A, Genedy M, El-Refai S, et al. The prevalence of hepatitis C virus infection in Egypt 2015: implications for future policy on prevention and treatment. Liver Int. 2017;37:45–53. - DOI

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