Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2021 Mar 12;72(Suppl 2):S95-S101.
doi: 10.1093/cid/ciaa1865.

Aspergillus Polymerase Chain Reaction-An Update on Technical Recommendations, Clinical Applications, and Justification for Inclusion in the Second Revision of the EORTC/MSGERC Definitions of Invasive Fungal Disease

P Lewis White  1 , Stephane Bretagne  2 , Angela M Caliendo  3 , Juergen Loeffler  4 , Thomas F Patterson  5 , Monica Slavin  6 , John R Wingard  7
Affiliations

Aspergillus Polymerase Chain Reaction-An Update on Technical Recommendations, Clinical Applications, and Justification for Inclusion in the Second Revision of the EORTC/MSGERC Definitions of Invasive Fungal Disease

P Lewis White et al. Clin Infect Dis. .

Abstract

Aspergillus polymerase chain reaction testing of blood and respiratory samples has recently been included in the second revision of the EORTC/MSGERC definitions for classifying invasive fungal disease. This is a result of considerable efforts to standardize methodology, the availability of commercial assays and external quality control programs, and additional clinical validation. This supporting article provides both clinical and technical justifications for its inclusion while also summarizing recent advances and likely future developments in the molecular diagnosis of invasive aspergillosis.

Keywords: Aspergillus PCR; EORTC/MSGERC definitions; clinical performance; technical aspects.

PubMed Disclaimer

Similar articles

See all similar articles

Cited by

See all "Cited by" articles