doi: 10.1016/j.tcb.2021.02.001.
Epub 2021 Feb 26.
Metabolic Regulation of Intestinal Stem Cell Homeostasis
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- PMID: 33648839
- DOI: 10.1016/j.tcb.2021.02.001
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Metabolic Regulation of Intestinal Stem Cell Homeostasis
Trends Cell Biol.
2021 May.
Abstract
The balance between self-renewal and differentiation of intestinal stem cells is essential for intestinal epithelial homeostasis, which can be regulated by dietary cues. Recent evidences indicate that metabolic pathways sense changes in nutritional status to control stem cell fate, which may provide new clues for the prevention of intestinal diseases.
Keywords: differentiation, nutrition; intestinal stem cells; metabolic pathways; self-renewal.
Copyright © 2021 Elsevier Ltd. All rights reserved.
Conflict of interest statement
Declaration of Interests The authors declare no competing interests.
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