Aspergillosis, Avian Species and the One Health Perspective: The Possible Importance of Birds in Azole Resistance
- PMID: 33352774
- PMCID: PMC7767009
- DOI: 10.3390/microorganisms8122037
Aspergillosis, Avian Species and the One Health Perspective: The Possible Importance of Birds in Azole Resistance
Abstract
The One Health context considers health based on three pillars: humans, animals, and environment. This approach is a strong ally in the surveillance of infectious diseases and in the development of prevention strategies. Aspergillus spp. are fungi that fit substantially in this context, in view of their ubiquity, as well as their importance as plant pathogens, and potentially fatal pathogens for, particularly, humans and avian species. In addition, the emergence of azole resistance, mainly in Aspergillus fumigatus sensu stricto, and the proven role of fungicides widely used on crops, reinforces the need for a multidisciplinary approach to this problem. Avian species are involved in short and long distance travel between different types of landscapes, such as agricultural fields, natural environments and urban environments. Thus, birds can play an important role in the dispersion of Aspergillus, and of special concern, azole-resistant strains. In addition, some bird species are particularly susceptible to aspergillosis. Therefore, avian aspergillosis could be considered as an environmental health indicator. In this review, aspergillosis in humans and birds will be discussed, with focus on the presence of Aspergillus in the environment. We will relate these issues with the emergence of azole resistance on Aspergillus. These topics will be therefore considered and reviewed from the "One Health" perspective.
Keywords: Aspergillus; One Health context; avian aspergillosis; azole resistance; invasive aspergillosis.
Conflict of interest statement
The authors declare no conflict of interest. The funders had no role in the design of the study; in the collection, analyses, or interpretation of data; in the writing of the manuscript, or in the decision to publish the results.
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References
-
- Seyedmousavi S., Guillot J., Arné P., De Hoog G.S., Mouton J.W., Melchers W.J.G., Verweij P.E. Aspergillus and aspergillosis in wild and domestic animals: A global health concern with parallels to human disease. Med. Mycol. 2015;53:765–797. - PubMed
-
- Marr K.A., Patterson T., Denning D. Aspergillosis pathogenesis, clinical manifestations, and therapy. Infect. Dis. Clin. N. Am. 2002;16:875–894. - PubMed
-
- Cacciuttolo E., Rossi G., Nardoni S., Legrottaglie R., Mani P. Anatomopathological aspects of avian aspergillosis. Vet. Res. Commun. 2009;33:521–527. - PubMed
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