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. 2020 Nov 3;12(1):96.
doi: 10.1186/s13098-020-00605-4.

The prevalence of metabolic syndrome in cardiovascular patients in Iran: a systematic review and meta-analysis

Nader Salari  1 , Peyman Kaikhosro Doulatyari  2 , Alireza Daneshkhah  3 , Aliakbar Vaisi-Raygani  4 , Rostam Jalali  4 , Parnian Kord Jamshidi  5 , Alireza Abdi  4 , Masoud Mohammadi  6 , Mohsen Kazeminia  7
Affiliations

The prevalence of metabolic syndrome in cardiovascular patients in Iran: a systematic review and meta-analysis

Nader Salari et al. Diabetol Metab Syndr. .

Abstract

Background: Cardiovascular disease is the cause of more than 50% of mortalities globally, and this rate has grown by 8.6% since the 60 s. One of the risk factors associated with cardiovascular disease and its resulting mortality rate is the metabolic syndrome. Different studies have reported inconsistent rates for the metabolic syndrome. However, no comprehensive study has been conducted to combine the results of existing studies. Thus, the present study was performed with the aim of determining the prevalence of metabolic syndrome among cardiovascular patients in Iran through a systematic review and meta-analysis.

Method: In this review study, the Scientific Information Database, Google Scholar, Science Direct, Scopus, PubMed, and Web of Science (ISI), databases were searched from January 2005 and until May 2020, to identify and extract related articles. To conduct the analysis, a random effects model was used, and the heterogeneity of the studies was examined using the I2 index. Data analysis was performed within Comprehensive Meta-Analysis (version 2) software.

Results: The prevalence of metabolic syndrome in cardiovascular patients in Iran in the 27 papers examined with a sample size of 44,735 patients was 34.2% (95% CI: 26.8-42.6%). A sensitivity analysis was performed to ensure the stability of the results, these results show that by omitting the prevalence from each study, the overall prevalence (34.2%) does not change significantly. the highest prevalence of metabolic syndrome in studies conducted in the period between 2015 and 2020, and this was reported as 55.3 (95% CI: 47.9-62.3) and the highest prevalence of metabolic syndrome in studies conducted in the methods of diagnosis IDF, and the rate was reported as 48 (95% CI: 36.5-59.8). based on meta-regression as the year of research increased, the prevalence of metabolic syndrome in cardiovascular patients in Iran also increased. However, with the increase in sample size, this prevalence decreased (p < 0.05).

Conclusions: The results of this study indicate that metabolic syndrome is high in cardiovascular patients in Iran. Accordingly, by understanding its etiology and supervision at all levels, suitable solutions could be offered by providing feedback to hospitals.

Keywords: Iran; Metabolic syndrome; cardiovascular; meta-analysis; prevalence.

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Conflict of interest statement

The authors declare that they have no conflict of interest.

Figures

Fig. 1
Fig. 1
Flow diagram of study selection
Fig. 2
Fig. 2
Funnel plot of the results related to the prevalence of metabolic syndrome cardiovascular patients in Iran
Fig. 3
Fig. 3
Prevalence of metabolic syndrome in cardiovascular patients and confidence interval 95% in Iran
Fig. 4
Fig. 4
Results of sensitivity analysis
Fig. 5
Fig. 5
Meta-regression of the relationship between the sample size and prevalence of metabolic syndrome in cardiovascular patients in Iran
Fig. 6
Fig. 6
Meta-regression of the relationship between the year of the study and prevalence of metabolic syndrome in cardiovascular patients in Iran
See this image and copyright information in PMC

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