Group B streptococcus vaccines: one step further

doi:10.1016/S1473-3099(20)30451-5

Comment

. 2021 Feb;21(2):158-160.

doi: 10.1016/S1473-3099(20)30451-5. Epub 2020 Sep 3.

Group B streptococcus vaccines: one step further

Reinhard Berner¹

Affiliations

Affiliation

¹ Department of Pediatrics, University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden 01307, Germany. Electronic address: reinhard.berner@uniklinikum-dresden.de.

PMID: 32891192
PMCID: PMC7470735
DOI: 10.1016/S1473-3099(20)30451-5

Comment

Group B streptococcus vaccines: one step further

Reinhard Berner. Lancet Infect Dis. 2021 Feb.

. 2021 Feb;21(2):158-160.

doi: 10.1016/S1473-3099(20)30451-5. Epub 2020 Sep 3.

Author

Reinhard Berner¹

Affiliation

¹ Department of Pediatrics, University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden 01307, Germany. Electronic address: reinhard.berner@uniklinikum-dresden.de.

PMID: 32891192
PMCID: PMC7470735
DOI: 10.1016/S1473-3099(20)30451-5

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Safety and immunogenicity of a novel hexavalent group B streptococcus conjugate vaccine in healthy, non-pregnant adults: a phase 1/2, randomised, placebo-controlled, observer-blinded, dose-escalation trial.
Absalon J, Segall N, Block SL, Center KJ, Scully IL, Giardina PC, Peterson J, Watson WJ, Gruber WC, Jansen KU, Peng Y, Munson S, Pavliakova D, Scott DA, Anderson AS. Absalon J, et al. Lancet Infect Dis. 2021 Feb;21(2):263-274. doi: 10.1016/S1473-3099(20)30478-3. Epub 2020 Sep 3. Lancet Infect Dis. 2021. PMID: 32891191 Free PMC article. Clinical Trial.

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References

1. Absalon J, Segall N, Block SL. Safety and immunogenicity of a novel hexavalent group B streptococcus conjugate vaccine in healthy non-pregnant adults: a phase 1/2, randomised, placebo-controlled, observer-blinded trial. Lancet Infect Dis. 2020 doi: 10.1016/S1473-3099(20)30478-3. published online Sept 3. - DOI - PMC - PubMed
1. Nanduri SA, Petit S, Smelser C. Epidemiology of invasive early-onset and late-onset group B streptococcal disease in the United States, 2006 to 2015: multistate laboratory and population-based surveillance. JAMA Pediatr. 2019;173:224–233. - PMC - PubMed
1. Francois Watkins LK, McGee L, Schrag SJ. Epidemiology of invasive group B streptococcal infections among nonpregnant adults in the United States, 2008–2016. JAMA Intern Med. 2019;179:479–488. - PMC - PubMed
1. Zürn K, Lander F, Hufnagel M, Monecke S, Berner R. Microarray analysis of group B streptococci causing invasive neonatal early- and late-onset infection. Pediatr Infect Dis J. 2020;39:449–453. - PubMed
1. Baker CJ, Rench MA, Edwards MS, Carpenter RJ, Hays BM, Kasper DL. Immunization of pregnant women with a polysaccharide vaccine of group B streptococcus. N Engl J Med. 1988;319:1180–1185. - PubMed

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[1] Absalon J, Segall N, Block SL. Safety and immunogenicity of a novel hexavalent group B streptococcus conjugate vaccine in healthy non-pregnant adults: a phase 1/2, randomised, placebo-controlled, observer-blinded trial. Lancet Infect Dis. 2020 doi: 10.1016/S1473-3099(20)30478-3. published online Sept 3. - DOI - PMC - PubMed

[2] Absalon J, Segall N, Block SL. Safety and immunogenicity of a novel hexavalent group B streptococcus conjugate vaccine in healthy non-pregnant adults: a phase 1/2, randomised, placebo-controlled, observer-blinded trial. Lancet Infect Dis. 2020 doi: 10.1016/S1473-3099(20)30478-3. published online Sept 3. - DOI - PMC - PubMed

[3] Nanduri SA, Petit S, Smelser C. Epidemiology of invasive early-onset and late-onset group B streptococcal disease in the United States, 2006 to 2015: multistate laboratory and population-based surveillance. JAMA Pediatr. 2019;173:224–233. - PMC - PubMed

[4] Nanduri SA, Petit S, Smelser C. Epidemiology of invasive early-onset and late-onset group B streptococcal disease in the United States, 2006 to 2015: multistate laboratory and population-based surveillance. JAMA Pediatr. 2019;173:224–233. - PMC - PubMed

[5] Francois Watkins LK, McGee L, Schrag SJ. Epidemiology of invasive group B streptococcal infections among nonpregnant adults in the United States, 2008–2016. JAMA Intern Med. 2019;179:479–488. - PMC - PubMed

[6] Francois Watkins LK, McGee L, Schrag SJ. Epidemiology of invasive group B streptococcal infections among nonpregnant adults in the United States, 2008–2016. JAMA Intern Med. 2019;179:479–488. - PMC - PubMed

[7] Zürn K, Lander F, Hufnagel M, Monecke S, Berner R. Microarray analysis of group B streptococci causing invasive neonatal early- and late-onset infection. Pediatr Infect Dis J. 2020;39:449–453. - PubMed

[8] Zürn K, Lander F, Hufnagel M, Monecke S, Berner R. Microarray analysis of group B streptococci causing invasive neonatal early- and late-onset infection. Pediatr Infect Dis J. 2020;39:449–453. - PubMed

[9] Baker CJ, Rench MA, Edwards MS, Carpenter RJ, Hays BM, Kasper DL. Immunization of pregnant women with a polysaccharide vaccine of group B streptococcus. N Engl J Med. 1988;319:1180–1185. - PubMed

[10] Baker CJ, Rench MA, Edwards MS, Carpenter RJ, Hays BM, Kasper DL. Immunization of pregnant women with a polysaccharide vaccine of group B streptococcus. N Engl J Med. 1988;319:1180–1185. - PubMed

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Group B streptococcus vaccines: one step further

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Group B streptococcus vaccines: one step further

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