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. 2020 Jan-Mar;16(1):110-111.
doi: 10.4183/aeb.2020.110.

A case of Inappropriate Antidiuretic Hormone Secretion Syndrome Associated with COVID-19 Pneumonia

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A case of Inappropriate Antidiuretic Hormone Secretion Syndrome Associated with COVID-19 Pneumonia

E Gemcioglu et al. Acta Endocrinol (Buchar). 2020 Jan-Mar.

Abstract

At the end of 2019, a novel coronavirus was identified as the cause of a cluster of pneumonia in China and it spread quickly to other countries. Although Covid-19 causes severe pneumonia, it is known that it can be associated with different diseases and prognosis of disease can be due to many of disorders such as hyponatremia. A 65-year-old female patient with sarcoidosis, cronic obstructive lung disease, hypertension and congestive heart failure presented to the emergency department with shortness of breath and fever. Oropharyngeal swab for Covid-19 PCR test was positive. After the initiation of treatment, the patient developed hyponatremia. This case is remarkable because there is no reported case of Covid-19 and inappropriate ADH syndrome coexistence and it demonstrates that there may be a correlation between Covid-19 infection prognosis and hyponatremia.

Keywords: Covid-19; Inappropriate Antidiuretic Hormone Secretion Syndrome (SIADH).

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Figures

Figure 1.
Figure 1.
Chronic fibrotic modifications due to chronic pulmonary disease and peripherally located ground glass opacities both of right and left lungs.

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References

    1. Hong X, Chi Z, Liu G, Huang H, Guo S, Fan J, Lin X, Qu L, Chen R, Wu L, Wang L, Zhang Q, Wu S, Pan Z, Lin H, Zhou Y, Zhang Y. Analysis of early renal injury in COVID-19 and diagnostic value of multi-index combined detection. MedRxiv. 2020:1–23. .03.07.20032599:
    1. Rose BD, Post TW. 5th ed. New York: McGrawHill; 2001. Clinical Physiology of Acid-Base and Electrolyte Disorders; pp. 703–761.
    1. Johnson BE, Chute JP, Rushin J, Williams J, Le PT, Venzon D, Richardson GE. A prospective study of patients with lung cancer and hyponatremia of malignancy. Am J Respir Crit Care Med. 1997;156(5):1669–1678. - PubMed
    1. Weissman PN, Shenkman L, Gregerman RI. Chlorpropamide hyponatremia: drug-induced inappropriate antidiuretic-hormone activity. N Engl J Med. 1971;284(2):65–71. - PubMed
    1. Fieldman NR, Forsling ML, Le Quesne LP. The effect of vasopressin on solute and water excretion during and after surgical operations. Ann Surg. 1985;201(3):383–390. - PMC - PubMed

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