Endothelial cell dysfunction: a major player in SARS-CoV-2 infection (COVID-19)?
- PMID: 32554538
- PMCID: PMC7301835
- DOI: 10.1183/13993003.01634-2020
Endothelial cell dysfunction: a major player in SARS-CoV-2 infection (COVID-19)?
Abstract
Endothelial cell dysfunction and impaired microcirculatory function contribute markedly to life-threatening complications of COVID-19, such as venous thromboembolic disease and multiple organ involvement
Conflict of interest statement
Conflict of interest: A. Huertas has nothing to disclose. Conflict of interest: D. Montani reports grants and personal fees from Actelion and Bayer, personal fees from GSK, Pfizer, Chiesi and Boehringer, grants, personal fees and non-financial support from MSD, non-financial support from Acceleron, outside the submitted work. Conflict of interest: L. Savale reports personal fees and non-financial support from Actelion and Bayer, grants and personal fees from GSK, outside the submitted work. Conflict of interest: J. Pichon has nothing to disclose. Conflict of interest: L. Tu has nothing to disclose. Conflict of interest: F. Parent reports grants from Bayer, CSL Behring and Sanofi, outside the submitted work. Conflict of interest: C. Guignabert has nothing to disclose. Conflict of interest: M. Humbert reports grants and personal fees from Actelion, Bayer, GSK and Acceleron, personal fees from Merck and United Therapeutics, outside the submitted work.
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Comment in
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Endothelial to mesenchymal transition: a precursor to post-COVID-19 interstitial pulmonary fibrosis and vascular obliteration?Eur Respir J. 2020 Oct 15;56(4):2003167. doi: 10.1183/13993003.03167-2020. Print 2020 Oct. Eur Respir J. 2020. PMID: 32859681 Free PMC article.
Comment on
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Venous thromboembolism in SARS-CoV-2 patients: only a problem in ventilated ICU patients, or is there more to it?Eur Respir J. 2020 Jul 30;56(1):2001201. doi: 10.1183/13993003.01201-2020. Print 2020 Jul. Eur Respir J. 2020. PMID: 32398294 Free PMC article.
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Pulmonary embolism in patients with COVID-19 pneumonia.Eur Respir J. 2020 Jul 30;56(1):2001365. doi: 10.1183/13993003.01365-2020. Print 2020 Jul. Eur Respir J. 2020. PMID: 32398297 Free PMC article.
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