Acute symptomatic hyponatremia in setting of SIADH as an isolated presentation of COVID-19

doi:10.1016/j.idcr.2020.e00859

Case Reports

. 2020 Jun 1:21:e00859.

doi: 10.1016/j.idcr.2020.e00859. eCollection 2020.

Acute symptomatic hyponatremia in setting of SIADH as an isolated presentation of COVID-19

Mhd Baraa Habib¹, Sundus Sardar¹, Jamal Sajid²

Affiliations

¹ Internal Medicine Residency Program, Internal Medicine Department, Hamad Medical Corporation, Doha, Qatar.
² Internal Medicine Department, Hamad Medical Corporation, Doha, Qatar.

PMID: 32523871
PMCID: PMC7263243
DOI: 10.1016/j.idcr.2020.e00859

Case Reports

Acute symptomatic hyponatremia in setting of SIADH as an isolated presentation of COVID-19

Mhd Baraa Habib et al. IDCases. 2020.

. 2020 Jun 1:21:e00859.

doi: 10.1016/j.idcr.2020.e00859. eCollection 2020.

Authors

Mhd Baraa Habib¹, Sundus Sardar¹, Jamal Sajid²

Affiliations

¹ Internal Medicine Residency Program, Internal Medicine Department, Hamad Medical Corporation, Doha, Qatar.
² Internal Medicine Department, Hamad Medical Corporation, Doha, Qatar.

PMID: 32523871
PMCID: PMC7263243
DOI: 10.1016/j.idcr.2020.e00859

Abstract

The syndrome of inappropriate secretion of antidiuretic hormone (SIADH) is one of the most common causes of hyponatremia in hospitalized patients. Wide spectrum of etiologies associated with hyponatremia pose significant challenges in detecting and treating this disorder. Several infectious causes of SIADH have been reported; however, hyponatremia associated with SIADH and Coronavirus disease 2019 (COVID-19) was only recently mentioned in a few case reports. We discuss a unique presentation of COVID-19, in which the patient presented with acute severe symptomatic hyponatremia thought to be the initial and isolated presentation of SARS-CoV-2 infection.

Keywords: Atypical presentation; COVID-19; COVID-19, Coronavirus disease 2019; ECG, electrocardiogram; Hyponatremia; Novel coronavirus; SARS-CoV-2 infection; SARS-CoV-2, severe acute respiratory syndrome coronavirus 2; SIADH; SIADH, syndrome of inappropriate antidiuretic hormone secretion.

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References

1. Decaux G., Musch W. Clinical laboratory evaluation of the syndrome of inappropriate secretion of antidiuretic hormone. Clin J Am Soc Nephrol. 2008;3(4):1175–1184. doi: 10.2215/CJN.04431007. - DOI - PubMed
1. Bulut C., Kato Y. Epidemiology of COVID-19. Turk J Med Sci. 2020;50(SI-1):563–570. doi: 10.3906/sag-2004-172. Published 2020 Apr 21. - DOI - PMC - PubMed
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[1] Decaux G., Musch W. Clinical laboratory evaluation of the syndrome of inappropriate secretion of antidiuretic hormone. Clin J Am Soc Nephrol. 2008;3(4):1175–1184. doi: 10.2215/CJN.04431007. - DOI - PubMed

[2] Decaux G., Musch W. Clinical laboratory evaluation of the syndrome of inappropriate secretion of antidiuretic hormone. Clin J Am Soc Nephrol. 2008;3(4):1175–1184. doi: 10.2215/CJN.04431007. - DOI - PubMed

[3] Bulut C., Kato Y. Epidemiology of COVID-19. Turk J Med Sci. 2020;50(SI-1):563–570. doi: 10.3906/sag-2004-172. Published 2020 Apr 21. - DOI - PMC - PubMed

[4] Bulut C., Kato Y. Epidemiology of COVID-19. Turk J Med Sci. 2020;50(SI-1):563–570. doi: 10.3906/sag-2004-172. Published 2020 Apr 21. - DOI - PMC - PubMed

[5] Ahn D.G., Shin H.J., Kim M.H. Current status of epidemiology, diagnosis, therapeutics, and vaccines for novel coronavirus disease 2019 (COVID-19) J Microbiol Biotechnol. 2020;30(3):313–324. doi: 10.4014/jmb.2003.03011. - DOI - PMC - PubMed

[6] Ahn D.G., Shin H.J., Kim M.H. Current status of epidemiology, diagnosis, therapeutics, and vaccines for novel coronavirus disease 2019 (COVID-19) J Microbiol Biotechnol. 2020;30(3):313–324. doi: 10.4014/jmb.2003.03011. - DOI - PMC - PubMed

[7] Fang F., Luo X. Facing a major outbreak of new coronavirus infections in 2019: thoughts of pediatricians. Chin J Ped. 2020;58(2):81–85. doi: 10.3760/cma.j.issn.0578-1310.2020.02.001. http://www.aimjournal.ir/PDF/aim-23-268.pdf - DOI - PubMed

[8] Fang F., Luo X. Facing a major outbreak of new coronavirus infections in 2019: thoughts of pediatricians. Chin J Ped. 2020;58(2):81–85. doi: 10.3760/cma.j.issn.0578-1310.2020.02.001. http://www.aimjournal.ir/PDF/aim-23-268.pdf - DOI - PubMed

[9] Kakodkar P., Kaka N., Baig M.N. A comprehensive literature review on the clinical presentation, and management of the pandemic coronavirus disease 2019 (COVID-19) Cureus. 2020;12(4) doi: 10.7759/cureus.7560. Published 2020 Apr 6. - DOI - PMC - PubMed

[10] Kakodkar P., Kaka N., Baig M.N. A comprehensive literature review on the clinical presentation, and management of the pandemic coronavirus disease 2019 (COVID-19) Cureus. 2020;12(4) doi: 10.7759/cureus.7560. Published 2020 Apr 6. - DOI - PMC - PubMed

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Acute symptomatic hyponatremia in setting of SIADH as an isolated presentation of COVID-19

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Acute symptomatic hyponatremia in setting of SIADH as an isolated presentation of COVID-19

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