Hyper-inflammatory Syndrome in a Child With COVID-19 Treated Successfully With Intravenous Immunoglobulin and Tocilizumab

doi:10.1007/s13312-020-1901-z

Case Reports

. 2020 Jul 15;57(7):681-683.

doi: 10.1007/s13312-020-1901-z. Epub 2020 May 10.

Hyper-inflammatory Syndrome in a Child With COVID-19 Treated Successfully With Intravenous Immunoglobulin and Tocilizumab

S Balasubramanian¹, T M Nagendran², B Ramachandran³, A V Ramanan⁴

Affiliations

¹ Department of Pediatrics, Kanchi Kamakoti CHILDS Trust Hospital, Chennai, India.
² Pediatric Intensive Care Unit, Kanchi Kamakoti CHILDS Trust Hospital, Chennai, India. nagupeds@gmail.com.
³ Pediatric Intensive Care Unit, Kanchi Kamakoti CHILDS Trust Hospital, Chennai, India.
⁴ Department of Pediatric Rheumatology; Bristol Royal Hospital for Children, Bristol, UK and Translational Health Sciences, University of Bristol, UK.

PMID: 32393681
PMCID: PMC7387261
DOI: 10.1007/s13312-020-1901-z

Case Reports

Hyper-inflammatory Syndrome in a Child With COVID-19 Treated Successfully With Intravenous Immunoglobulin and Tocilizumab

S Balasubramanian et al. Indian Pediatr. 2020.

. 2020 Jul 15;57(7):681-683.

doi: 10.1007/s13312-020-1901-z. Epub 2020 May 10.

Authors

S Balasubramanian¹, T M Nagendran², B Ramachandran³, A V Ramanan⁴

Affiliations

¹ Department of Pediatrics, Kanchi Kamakoti CHILDS Trust Hospital, Chennai, India.
² Pediatric Intensive Care Unit, Kanchi Kamakoti CHILDS Trust Hospital, Chennai, India. nagupeds@gmail.com.
³ Pediatric Intensive Care Unit, Kanchi Kamakoti CHILDS Trust Hospital, Chennai, India.
⁴ Department of Pediatric Rheumatology; Bristol Royal Hospital for Children, Bristol, UK and Translational Health Sciences, University of Bristol, UK.

PMID: 32393681
PMCID: PMC7387261
DOI: 10.1007/s13312-020-1901-z

No abstract available

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Conflict of interest statement

Competing interest: None stated.

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References

1. RCPCH. Guidance — Paediatric multisystem inflammatory syndrome temporally associated with COVID-19.Available from: https://www.rcpch.ac.uk/resources/guidance-paediatric-multisystem-inflam.... Accessed May 02, 2020.
1. Balasubramanian S, Rao NM, Goenka A, Roderick M, Ramanan AV. Coronavirus Disease (COVID-19) in Children — What We Know So Far and What We Do Not?. Indian Pediatr.2020 Apr 9 [Epub ahead of print]. Available from:https://www.indianpediatrics.net/COVID29.03.2020/SA-00159.pdf. Accessed May 09, 2020. - PMC - PubMed
1. Riphagen S, Gomez X, Gonzalez-Martinez C, Wilkinson N, Theocharis P. Hyperinflammatory shock in children during COVID-19 pandemic. Lancet. 2020 May 07. [Epub ahead of print]. Available from: https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(20)31094.... Accessed on May 09, 2020. - PMC - PubMed
1. Ye Q, Wang B, Mao J. The pathogenesis and treatment of the ‘Cytokine Storm’ in COVID-19. J Infect. 2020 Apr 10. [Epub ahead of print]. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7194613/pdf/main.pdf. Accessed May 09, 2020. - PMC - PubMed
1. Huang C, Wang Y, Li X, Ren L, Zhao J, Hu Y, et al. Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China. Lancet. 2020;395:497–506. doi: 10.1016/S0140-6736(20)30183-5. - DOI - PMC - PubMed

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[1] RCPCH. Guidance — Paediatric multisystem inflammatory syndrome temporally associated with COVID-19.Available from: https://www.rcpch.ac.uk/resources/guidance-paediatric-multisystem-inflam.... Accessed May 02, 2020.

[2] RCPCH. Guidance — Paediatric multisystem inflammatory syndrome temporally associated with COVID-19.Available from: https://www.rcpch.ac.uk/resources/guidance-paediatric-multisystem-inflam.... Accessed May 02, 2020.

[3] Balasubramanian S, Rao NM, Goenka A, Roderick M, Ramanan AV. Coronavirus Disease (COVID-19) in Children — What We Know So Far and What We Do Not?. Indian Pediatr.2020 Apr 9 [Epub ahead of print]. Available from:https://www.indianpediatrics.net/COVID29.03.2020/SA-00159.pdf. Accessed May 09, 2020. - PMC - PubMed

[4] Balasubramanian S, Rao NM, Goenka A, Roderick M, Ramanan AV. Coronavirus Disease (COVID-19) in Children — What We Know So Far and What We Do Not?. Indian Pediatr.2020 Apr 9 [Epub ahead of print]. Available from:https://www.indianpediatrics.net/COVID29.03.2020/SA-00159.pdf. Accessed May 09, 2020. - PMC - PubMed

[5] Riphagen S, Gomez X, Gonzalez-Martinez C, Wilkinson N, Theocharis P. Hyperinflammatory shock in children during COVID-19 pandemic. Lancet. 2020 May 07. [Epub ahead of print]. Available from: https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(20)31094.... Accessed on May 09, 2020. - PMC - PubMed

[6] Riphagen S, Gomez X, Gonzalez-Martinez C, Wilkinson N, Theocharis P. Hyperinflammatory shock in children during COVID-19 pandemic. Lancet. 2020 May 07. [Epub ahead of print]. Available from: https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(20)31094.... Accessed on May 09, 2020. - PMC - PubMed

[7] Ye Q, Wang B, Mao J. The pathogenesis and treatment of the ‘Cytokine Storm’ in COVID-19. J Infect. 2020 Apr 10. [Epub ahead of print]. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7194613/pdf/main.pdf. Accessed May 09, 2020. - PMC - PubMed

[8] Ye Q, Wang B, Mao J. The pathogenesis and treatment of the ‘Cytokine Storm’ in COVID-19. J Infect. 2020 Apr 10. [Epub ahead of print]. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7194613/pdf/main.pdf. Accessed May 09, 2020. - PMC - PubMed

[9] Huang C, Wang Y, Li X, Ren L, Zhao J, Hu Y, et al. Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China. Lancet. 2020;395:497–506. doi: 10.1016/S0140-6736(20)30183-5. - DOI - PMC - PubMed

[10] Huang C, Wang Y, Li X, Ren L, Zhao J, Hu Y, et al. Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China. Lancet. 2020;395:497–506. doi: 10.1016/S0140-6736(20)30183-5. - DOI - PMC - PubMed

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Hyper-inflammatory Syndrome in a Child With COVID-19 Treated Successfully With Intravenous Immunoglobulin and Tocilizumab

Affiliations

Hyper-inflammatory Syndrome in a Child With COVID-19 Treated Successfully With Intravenous Immunoglobulin and Tocilizumab

Authors

Affiliations

Conflict of interest statement

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