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Editorial
. 2020 Jul;146(1):67-69.
doi: 10.1016/j.jaci.2020.04.030. Epub 2020 May 1.

Perspective: COVID-19, implications of nasal diseases and consequences for their management

Li Jian  1 , Wei Yi  1 , Nan Zhang  2 , Weiping Wen  1 , Olga Krysko  2 , Woo-Jung Song  3 , Claus Bachert  4
Affiliations
Editorial

Perspective: COVID-19, implications of nasal diseases and consequences for their management

Li Jian et al. J Allergy Clin Immunol. 2020 Jul.
No abstract available

Keywords: COVID-19; SARS-CoV-2; allergy; biologics; chronic rhinosinusitis; corticosteroids.

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Figures

Fig 1
Fig 1
SARS-CoV-2 binds to ACE2 expressed on human airway cells; the activation of the serine protease TMPRSS2 activates the spike protein to allow virus-cell fusion and cell entry. Regulation of ACE2 in upper airway disease and by corticosteroid treatment is largely unknown, but may offer a chance for intervention.
See this image and copyright information in PMC

Comment in

Comment on

  • Intranasal corticosteroids in allergic rhinitis in COVID-19 infected patients: An ARIA-EAACI statement.
    Bousquet J, Akdis CA, Jutel M, Bachert C, Klimek L, Agache I, Ansotegui IJ, Bedbrook A, Bosnic-Anticevich S, Canonica GW, Chivato T, Cruz AA, Czarlewski W, Del Giacco S, Du H, Fonseca JA, Gao Y, Haahtela T, Hoffmann-Sommergruber K, Ivancevich JC, Khaltaev N, Knol EF, Kuna P, Larenas-Linnemann D, Mullol J, Naclerio R, Ohta K, Okamoto Y, O'Mahony L, Onorato GL, Papadopoulos NG, Pfaar O, Samolinski B, Schwarze J, Toppila-Salmi S, Ventura MT, Valiulis A, Yorgancioglu A, Zuberbier T, Pawankar R; ARIA-MASK Study Group. Bousquet J, et al. Allergy. 2020 Oct;75(10):2440-2444. doi: 10.1111/all.14302. Allergy. 2020. PMID: 32233040 No abstract available.

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