Characteristics of pediatric SARS-CoV-2 infection and potential evidence for persistent fecal viral shedding
- PMID: 32284613
- PMCID: PMC7095102
- DOI: 10.1038/s41591-020-0817-4
Characteristics of pediatric SARS-CoV-2 infection and potential evidence for persistent fecal viral shedding
Abstract
We report epidemiological and clinical investigations on ten pediatric SARS-CoV-2 infection cases confirmed by real-time reverse transcription PCR assay of SARS-CoV-2 RNA. Symptoms in these cases were nonspecific and no children required respiratory support or intensive care. Chest X-rays lacked definite signs of pneumonia, a defining feature of the infection in adult cases. Notably, eight children persistently tested positive on rectal swabs even after nasopharyngeal testing was negative, raising the possibility of fecal-oral transmission.
Conflict of interest statement
The authors declare no competing interests.
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Comment in
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COVID-19: faecal-oral transmission?Nat Rev Gastroenterol Hepatol. 2020 May;17(5):259. doi: 10.1038/s41575-020-0295-7. Nat Rev Gastroenterol Hepatol. 2020. PMID: 32214231 Free PMC article. No abstract available.
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References
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- Coronavirus Disease (COVID-2019) Situation Report 36 (WHO, 2020).
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