Can angiotensin receptor-blocking drugs perhaps be harmful in the COVID-19 pandemic?

doi:10.1097/HJH.0000000000002450

. 2020 May;38(5):781-782.

doi: 10.1097/HJH.0000000000002450.

Can angiotensin receptor-blocking drugs perhaps be harmful in the COVID-19 pandemic?

Murray Esler¹, Danielle Esler²

Affiliations

¹ Baker Heart and Diabetes Institute.
² Public Health Directorate, Northern Territory Department of Health, and Honorary Research Fellow Baker Heart and Diabetes Institute, Melbourne, Australia.

PMID: 32195824
DOI: 10.1097/HJH.0000000000002450

Can angiotensin receptor-blocking drugs perhaps be harmful in the COVID-19 pandemic?

Murray Esler et al. J Hypertens. 2020 May.

. 2020 May;38(5):781-782.

doi: 10.1097/HJH.0000000000002450.

Authors

Murray Esler¹, Danielle Esler²

Affiliations

¹ Baker Heart and Diabetes Institute.
² Public Health Directorate, Northern Territory Department of Health, and Honorary Research Fellow Baker Heart and Diabetes Institute, Melbourne, Australia.

PMID: 32195824
DOI: 10.1097/HJH.0000000000002450

No abstract available

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Comment in

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Sunden-Cullberg J. Sunden-Cullberg J. Hypertension. 2020 Jun;75(6):e15-e16. doi: 10.1161/HYPERTENSIONAHA.120.15178. Epub 2020 Apr 10. Hypertension. 2020. PMID: 32275190 Free PMC article. No abstract available.
Switching to another antihypertensive effective drug when using ACEIs/ARBs to treat arterial hypertension during COVID-19.
Ciulla MM. Ciulla MM. Eur Heart J. 2020 May 14;41(19):1856. doi: 10.1093/eurheartj/ehaa331. Eur Heart J. 2020. PMID: 32324222 Free PMC article. No abstract available.
Comment on 'Can angiotensin receptor-blocking drugs perhaps be harmful in the COVID-19 pandemic?'.
Cüre E, Cumhur Cüre M. Cüre E, et al. J Hypertens. 2020 Jun;38(6):1189-1198. doi: 10.1097/HJH.0000000000002481. J Hypertens. 2020. PMID: 32371810 Free PMC article. No abstract available.
Angiotensin-converting enzyme inhibitors, angiotensin II receptor blockers and coronavirus.
Verdecchia P, Angeli F, Reboldi G. Verdecchia P, et al. J Hypertens. 2020 Jun;38(6):1190-1191. doi: 10.1097/HJH.0000000000002469. J Hypertens. 2020. PMID: 32371811 Free PMC article. No abstract available.
COVID-19, hypertension and angiotensin receptor-blocking drugs.
Fernández-Fernández FJ. Fernández-Fernández FJ. J Hypertens. 2020 Jun;38(6):1191. doi: 10.1097/HJH.0000000000002468. J Hypertens. 2020. PMID: 32371812 Free PMC article. No abstract available.
Could renin-angiotensin-aldosterone system inhibitors be used for hypertensive patients with coronavirus disease 2019?
Liu D, Li YZ, Wu H. Liu D, et al. J Hypertens. 2020 Jun;38(6):1191-1192. doi: 10.1097/HJH.0000000000002474. J Hypertens. 2020. PMID: 32371813 Free PMC article. No abstract available.
Reply: Possible impact of membrane ACE2 expression on COVID-19 infection.
Esler M, Esler D. Esler M, et al. J Hypertens. 2020 Jun;38(6):1192-1194. doi: 10.1097/HJH.0000000000002484. J Hypertens. 2020. PMID: 32371814 Free PMC article. No abstract available.
Hypertension and predisposition to infection: an important issue during this global pandemic.
Moini N, Neef P. Moini N, et al. J Hypertens. 2020 Jun;38(6):1195-1196. doi: 10.1097/HJH.0000000000002471. J Hypertens. 2020. PMID: 32371816 Free PMC article. No abstract available.
Angiotensin-converting enzyme-2 in SARS-CoV-2 infection: good or bad?
Versmissen J, Verdonk K, Lafeber M, van den Akker JPC, Hunfeld NGM, Hoorn EJ, Danser AHJ. Versmissen J, et al. J Hypertens. 2020 Jun;38(6):1196-1197. doi: 10.1097/HJH.0000000000002472. J Hypertens. 2020. PMID: 32371817 Free PMC article. No abstract available.

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References

1. Zhou P, Yang X, Wang XG, Hu B, Zhang L, Zhang W, et al. A pneumonia outbreak associated with a new coronavirus of probable bat origin. Nature 2020; https://doi.org/10.1038/s41586-020-2012-7 - DOI
1. Zisman LS, Keller RS, Weaver B, Lin Q, Speth R, Bristow M, et al. Increased angiotensin-(1-7) forming activity in failing human heart ventricles: evidence for upregulation of the angiotensin-converting enzyme homologue ACE2. Circulation 2003; 108:1707–1712.
1. Gallagher PE, Ferrario CM, Tallant EA. MAP kinase/phosphatase pathway mediates the regulation of ACE2 by angiotensin peptides. Am J Physiol Cell Physiol 2008; 295:C1169–C1174.
1. Jessup JA, Gallagher PE, Averill DB, Brosnihan B, Tallant A, Chappell MC, et al. Effect of angiotension blockade on a new congenic model of hypertension derived from transgenic Ren-2 rats. Am J Physiol Heart Circ 2006; 291:H2166–H2172.
1. Ferrario CM, Jessup J, Chappell MC, Averill DB, Brosnihan KB, Tallant EA, et al. Effect of angiotensin-converting enzyme inhibition and angiotensin II receptor blockers on cardiac angiotensin-converting enzyme 2. Circulation 2005; 111:2605–2610.

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[1] Zhou P, Yang X, Wang XG, Hu B, Zhang L, Zhang W, et al. A pneumonia outbreak associated with a new coronavirus of probable bat origin. Nature 2020; https://doi.org/10.1038/s41586-020-2012-7 - DOI

[2] Zhou P, Yang X, Wang XG, Hu B, Zhang L, Zhang W, et al. A pneumonia outbreak associated with a new coronavirus of probable bat origin. Nature 2020; https://doi.org/10.1038/s41586-020-2012-7 - DOI

[3] Zisman LS, Keller RS, Weaver B, Lin Q, Speth R, Bristow M, et al. Increased angiotensin-(1-7) forming activity in failing human heart ventricles: evidence for upregulation of the angiotensin-converting enzyme homologue ACE2. Circulation 2003; 108:1707–1712.

[4] Zisman LS, Keller RS, Weaver B, Lin Q, Speth R, Bristow M, et al. Increased angiotensin-(1-7) forming activity in failing human heart ventricles: evidence for upregulation of the angiotensin-converting enzyme homologue ACE2. Circulation 2003; 108:1707–1712.

[5] Gallagher PE, Ferrario CM, Tallant EA. MAP kinase/phosphatase pathway mediates the regulation of ACE2 by angiotensin peptides. Am J Physiol Cell Physiol 2008; 295:C1169–C1174.

[6] Gallagher PE, Ferrario CM, Tallant EA. MAP kinase/phosphatase pathway mediates the regulation of ACE2 by angiotensin peptides. Am J Physiol Cell Physiol 2008; 295:C1169–C1174.

[7] Jessup JA, Gallagher PE, Averill DB, Brosnihan B, Tallant A, Chappell MC, et al. Effect of angiotension blockade on a new congenic model of hypertension derived from transgenic Ren-2 rats. Am J Physiol Heart Circ 2006; 291:H2166–H2172.

[8] Jessup JA, Gallagher PE, Averill DB, Brosnihan B, Tallant A, Chappell MC, et al. Effect of angiotension blockade on a new congenic model of hypertension derived from transgenic Ren-2 rats. Am J Physiol Heart Circ 2006; 291:H2166–H2172.

[9] Ferrario CM, Jessup J, Chappell MC, Averill DB, Brosnihan KB, Tallant EA, et al. Effect of angiotensin-converting enzyme inhibition and angiotensin II receptor blockers on cardiac angiotensin-converting enzyme 2. Circulation 2005; 111:2605–2610.

[10] Ferrario CM, Jessup J, Chappell MC, Averill DB, Brosnihan KB, Tallant EA, et al. Effect of angiotensin-converting enzyme inhibition and angiotensin II receptor blockers on cardiac angiotensin-converting enzyme 2. Circulation 2005; 111:2605–2610.

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Can angiotensin receptor-blocking drugs perhaps be harmful in the COVID-19 pandemic?

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Can angiotensin receptor-blocking drugs perhaps be harmful in the COVID-19 pandemic?

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