Viral load of SARS-CoV-2 in clinical samples

doi:10.1016/S1473-3099(20)30113-4

. 2020 Apr;20(4):411-412.

doi: 10.1016/S1473-3099(20)30113-4. Epub 2020 Feb 24.

Viral load of SARS-CoV-2 in clinical samples

Yang Pan¹, Daitao Zhang², Peng Yang¹, Leo L M Poon³, Quanyi Wang⁴

Affiliations

¹ Beijing Center for Disease Prevention and Control, Beijing 100013, China; Beijing Research Center for Preventive Medicine, Beijing, China; School of Public Health, Capital Medical University, Beijing, China.
² Beijing Center for Disease Prevention and Control, Beijing 100013, China; Beijing Research Center for Preventive Medicine, Beijing, China.
³ School of Public Health, LKS Faculty of Medicine, The University of Hong Kong, Hong Kong Special Administrative Region 999077, China. Electronic address: llmpoon@hku.hk.
⁴ Beijing Center for Disease Prevention and Control, Beijing 100013, China; Beijing Research Center for Preventive Medicine, Beijing, China. Electronic address: bjcdcxm@126.com.

PMID: 32105638
PMCID: PMC7128099
DOI: 10.1016/S1473-3099(20)30113-4

Viral load of SARS-CoV-2 in clinical samples

Yang Pan et al. Lancet Infect Dis. 2020 Apr.

. 2020 Apr;20(4):411-412.

doi: 10.1016/S1473-3099(20)30113-4. Epub 2020 Feb 24.

Authors

Yang Pan¹, Daitao Zhang², Peng Yang¹, Leo L M Poon³, Quanyi Wang⁴

Affiliations

¹ Beijing Center for Disease Prevention and Control, Beijing 100013, China; Beijing Research Center for Preventive Medicine, Beijing, China; School of Public Health, Capital Medical University, Beijing, China.
² Beijing Center for Disease Prevention and Control, Beijing 100013, China; Beijing Research Center for Preventive Medicine, Beijing, China.
³ School of Public Health, LKS Faculty of Medicine, The University of Hong Kong, Hong Kong Special Administrative Region 999077, China. Electronic address: llmpoon@hku.hk.
⁴ Beijing Center for Disease Prevention and Control, Beijing 100013, China; Beijing Research Center for Preventive Medicine, Beijing, China. Electronic address: bjcdcxm@126.com.

PMID: 32105638
PMCID: PMC7128099
DOI: 10.1016/S1473-3099(20)30113-4

No abstract available

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Figures

**Figure**
Viral dynamics of SARS-CoV-2 in infected patients Viral load (mean [SD]) from serial throat swab and sputum samples in patient 1 (A) and patient 2 (B). (C) Viral load (median [IQR]) in throat and sputum samples collected from 80 patients at different stages after disease onset. (D) Correlation between viral load in throat swab samples and viral load in sputum samples.

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Comment in

Profile of specific antibodies to SARS-CoV-2: The first report.
Xiao AT, Gao C, Zhang S. Xiao AT, et al. J Infect. 2020 Jul;81(1):147-178. doi: 10.1016/j.jinf.2020.03.012. Epub 2020 Mar 21. J Infect. 2020. PMID: 32209385 Free PMC article. No abstract available.

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References

1. Lu R, Zhao X, Li J. Genomic characterisation and epidemiology of 2019 novel coronavirus: implications for virus origins and receptor binding. Lancet. 2020 doi: 10.1016/S0140-6736(20)30251-8. published online Jan 30. - DOI - PMC - PubMed
1. WHO Laboratory testing for 2019 novel coronavirus (2019-nCoV) in suspected human cases. Interim guidance. Jan 17, 2020. https://www.who.int/publications-detail/laboratory-testing-for-2019-nove...
1. Chu DKW, Pan Y, Cheng SMS. Molecular diagnosis of a novel coronavirus (2019-nCoV) causing an outbreak of pneumonia. Clin Chem. 2020 doi: 10.1093/clinchem/hvaa029. published online Jan 31. - DOI - PMC - PubMed
1. Peiris JS, Chu CM, Cheng VC. Clinical progression and viral load in a community outbreak of coronavirus-associated SARS pneumonia: a prospective study. Lancet. 2003;361:1767–1772. - PMC - PubMed

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[1] Lu R, Zhao X, Li J. Genomic characterisation and epidemiology of 2019 novel coronavirus: implications for virus origins and receptor binding. Lancet. 2020 doi: 10.1016/S0140-6736(20)30251-8. published online Jan 30. - DOI - PMC - PubMed

[2] Lu R, Zhao X, Li J. Genomic characterisation and epidemiology of 2019 novel coronavirus: implications for virus origins and receptor binding. Lancet. 2020 doi: 10.1016/S0140-6736(20)30251-8. published online Jan 30. - DOI - PMC - PubMed

[3] WHO Laboratory testing for 2019 novel coronavirus (2019-nCoV) in suspected human cases. Interim guidance. Jan 17, 2020. https://www.who.int/publications-detail/laboratory-testing-for-2019-nove...

[4] WHO Laboratory testing for 2019 novel coronavirus (2019-nCoV) in suspected human cases. Interim guidance. Jan 17, 2020. https://www.who.int/publications-detail/laboratory-testing-for-2019-nove...

[5] Chu DKW, Pan Y, Cheng SMS. Molecular diagnosis of a novel coronavirus (2019-nCoV) causing an outbreak of pneumonia. Clin Chem. 2020 doi: 10.1093/clinchem/hvaa029. published online Jan 31. - DOI - PMC - PubMed

[6] Chu DKW, Pan Y, Cheng SMS. Molecular diagnosis of a novel coronavirus (2019-nCoV) causing an outbreak of pneumonia. Clin Chem. 2020 doi: 10.1093/clinchem/hvaa029. published online Jan 31. - DOI - PMC - PubMed

[7] Peiris JS, Chu CM, Cheng VC. Clinical progression and viral load in a community outbreak of coronavirus-associated SARS pneumonia: a prospective study. Lancet. 2003;361:1767–1772. - PMC - PubMed

[8] Peiris JS, Chu CM, Cheng VC. Clinical progression and viral load in a community outbreak of coronavirus-associated SARS pneumonia: a prospective study. Lancet. 2003;361:1767–1772. - PMC - PubMed

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Viral load of SARS-CoV-2 in clinical samples

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