doi: 10.1007/BF00695392.
Evidence for joint genic control of spontaneous mutation and genetic recombination during mitosis in Saccharomyces
- PMID: 320451
- DOI: 10.1007/BF00695392
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Evidence for joint genic control of spontaneous mutation and genetic recombination during mitosis in Saccharomyces
Mol Gen Genet.
.
Abstract
A procedure for detection of mutants exhibiting either enhanced or reduced spontaneous mutation during mitosis and/or meiosis has been developed to probe the joint genic control of spontaneous mutation and recombination in yeast. A semidominant mutator, rem1-1, recovered by this technique, exhibits enhanced spontaneous mutation,intragenic recombination, and intergenic recombination during mitosis. Diploids homozygous for rem1-1 exhibit normal levels of meiotic intragenic and intergenic recombination and diminished ascospore viability.
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