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Review
. 2020 Jul;108(5):1934-1952.
doi: 10.1002/jbm.b.34535. Epub 2019 Dec 30.

Current status and future outlook of nano-based systems for burn wound management

Morteza Abazari  1 , Azadeh Ghaffari  2   3 , Hamid Rashidzadeh  4 , Safa Momeni Badeleh  2 , Yaser Maleki  5
Affiliations
Review

Current status and future outlook of nano-based systems for burn wound management

Morteza Abazari et al. J Biomed Mater Res B Appl Biomater. 2020 Jul.

Abstract

Wound healing process is a natural and intricate response of the body to its injuries and includes a well-orchestrated sequence of biochemical and cellular phenomena to restore the integrity of skin and injured tissues. Complex nature and associated complications of burn wounds lead to an incomplete and prolonged recovery of these types of wounds. Among different materials and systems which have been used in treating the wounds, nanotechnology driven therapeutic systems showed a great opportunity to improvement and enhancement of the healing process of different type of wounds. The aim of this study is to provide an overview of the recent studies about the various nanotechnology-based management of burn wounds and the future outlook of these systems in this area. Laboratory and animal models for assessing the efficacy of these systems in burn wound management also discussed.

Keywords: burn wound; laboratory and animal models; multicomposites; nanomedicine; nanoparticles; nanotechnology-based systems; scaffolds.

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