Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2020 Apr;249(4):483-495.
doi: 10.1002/dvdy.139. Epub 2019 Dec 14.

Regulation of auxin transcriptional responses

Samantha K Powers  1 , Lucia C Strader  1   2   3
Affiliations
Review

Regulation of auxin transcriptional responses

Samantha K Powers et al. Dev Dyn. 2020 Apr.

Abstract

The plant hormone auxin acts as a signaling molecule to regulate a vast number of developmental responses throughout all stages of plant growth. Tight control and coordination of auxin signaling is required for the generation of specific auxin-response outputs. The nuclear auxin signaling pathway controls auxin-responsive gene transcription through the TRANSPORT INHIBITOR RESPONSE1/AUXIN SIGNALING F-BOX pathway. Recent work has uncovered important details into how regulation of auxin signaling components can generate unique and specific responses to determine auxin outputs. In this review, we discuss what is known about the core auxin signaling components and explore mechanisms important for regulating auxin response specificity.

Keywords: Arabidopsis thaliana; auxin; phytohormone; signal transduction.

PubMed Disclaimer

Conflict of interest statement

The authors declare no potential conflict of interest.

Figures

Figure 1
Figure 1
Auxin signaling through the SCFTIR1/AFB pathway. A, In the current auxin signaling model, auxin/indole‐3‐acetic acid (Aux/IAA) repressor proteins interact with and repress auxin response factor (ARF)‐mediated transcription. In the presence of auxin, transport inhibitor response 1 (TIR1) forms a co‐receptor complex with the Aux/IAA and targets it for degradation. Upon degradation of the Aux/IAA, the ARF transcription factor mediates auxin‐responsive transcription. B, Schematic of signaling component domain structures and their role in regulating auxin response
See this image and copyright information in PMC

Similar articles

See all similar articles

Cited by

See all "Cited by" articles

References

    1. Woodward AW, Bartel B. Auxin: regulation, action, and interaction. Ann Bot. 2005;95:707‐735. - PMC - PubMed
    1. Wang R, Estelle M. Diversity and specificity: auxin perception and signaling through the TIR1/AFB pathway. Curr Opin Plant Biol. 2014;21:51‐58. - PMC - PubMed
    1. Korasick DA, Jez JM, Strader LC. Refining the nuclear auxin response pathway through structural biology. Curr Opin Plant Biol. 2015b;27:22‐28. - PMC - PubMed
    1. Chapman EJ, Estelle M. Mechanism of auxin‐regulated gene expression in plants. Annu Rev Genet. 2009;43:265‐285. - PubMed
    1. Dharmasiri N, Dharmasiri S, Estelle M. The F‐box protein TIR1 is an auxin receptor. Nature. 2005a;435:441‐445. - PubMed

Publication types

MeSH terms

LinkOut - more resources