Case Reports
doi: 10.1002/ajmg.1320300140.
Inactivation pattern of the fragile X in heterozygous carriers
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- PMID: 3177460
- DOI: 10.1002/ajmg.1320300140
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Case Reports
Inactivation pattern of the fragile X in heterozygous carriers
Am J Med Genet.
1988 May-Jun.
Abstract
In this report we present new data on BrdU-inactivation studies in lymphocytes of five heterozygotes. The present data confirm our previous findings that the prediction of the mental status of female heterozygote carriers cannot be based on the X-inactivation pattern. The general tendency to carry the fragile site on the active X is confirmed and the results of previous studies and hypotheses are reviewed.
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