Distribution of neurotensin-like immunoreactivity in the central nervous system of the Formosan monkey
- PMID: 3149760
Distribution of neurotensin-like immunoreactivity in the central nervous system of the Formosan monkey
Abstract
The distribution of neurotensin-like immunoreactivity was investigated in the central nervous system of the Formosan monkey employing immunohistochemical techniques. Neurotensin-containing cells were found to be widely distributed in the forebrain. The principal densities of neurotensin-like neuronal perikarya were located in the limbic system, the basal ganglion and the cerebral cortex; particularly in the amygdala, the septum, the neostriatum, the claustrum and the insula. The stria terminalis and the preoptic area were also rich in immunostained neurotensin-like neurons. A large number of immunoreactive fibers were observed from the cerebral cortex to the spinal cord in locations such as the median eminence, the arcuate nucleus, the hippocampus, the central gray and the dorsal horn of the spinal cord. We analyzed in detail the distribution of neurotensin-like immunoreactivity in the brain of the Formosan monkey, and compared these results with those obtained in the brain of the rat, Japanese monkey and human. Some possible implications regarding differences in location of this peptide are also briefly discussed.
Similar articles
-
Distribution of FMRFamide-like immunoreactivity in the central nervous system of the Formosan monkey (Macaca cyclopsis).Peptides. 1989 Jul-Aug;10(4):825-34. doi: 10.1016/0196-9781(89)90121-6. Peptides. 1989. PMID: 2587424
-
The distribution of luteinizing hormone-releasing hormone (LHRH) neurons and fibers in the Formosan rock-monkey.Proc Natl Sci Counc Repub China B. 1988 Jul;12(3):156-62. Proc Natl Sci Counc Repub China B. 1988. PMID: 3149759
-
Distribution of neurotensin-containing neurons in the central nervous system of the pigeon and the chicken.J Comp Neurol. 1996 Nov 11;375(2):187-211. doi: 10.1002/(SICI)1096-9861(19961111)375:2<187::AID-CNE2>3.0.CO;2-Z. J Comp Neurol. 1996. PMID: 8915825
-
Distribution of neurotensin and its receptor in the central nervous system.Ann N Y Acad Sci. 1982;400:132-49. doi: 10.1111/j.1749-6632.1982.tb31565.x. Ann N Y Acad Sci. 1982. PMID: 6301323 Review. No abstract available.
-
The role of neurotensin in central nervous system pathophysiology: what is the evidence?J Psychiatry Neurosci. 2006 Jul;31(4):229-45. J Psychiatry Neurosci. 2006. PMID: 16862241 Free PMC article. Review.
Cited by
-
Activation of neurotensin receptor 1 facilitates neuronal excitability and spatial learning and memory in the entorhinal cortex: beneficial actions in an Alzheimer's disease model.J Neurosci. 2014 May 14;34(20):7027-42. doi: 10.1523/JNEUROSCI.0408-14.2014. J Neurosci. 2014. PMID: 24828655 Free PMC article.