doi: 10.1128/JVI.58.3.988-990.1986.
Induction of Epstein-Barr virus nuclear antigens
- PMID: 3084809
- PMCID: PMC253013
- DOI: 10.1128/JVI.58.3.988-990.1986
Item in Clipboard
Induction of Epstein-Barr virus nuclear antigens
J Virol.
1986 Jun.
Abstract
Lymphocytes were infected with the QIMR-WIL strain of Epstein-Barr virus, and the induction of Epstein-Barr virus-associated nuclear antigens was determined by using the protein immunoblot. There was a temporal increase in six antigens, with Epstein-Barr nuclear antigen 2 being detected 1 day after infection. The appearance of these antigens was shown to be independent of cellular DNA synthesis.
Similar articles
-
Blastogenic response and EBNA induction in human lymphocytes by Epstein-Barr virus only requires B cells but not macrophages.Cancer Lett. 1977 Mar;2(4-5):217-20. doi: 10.1016/s0304-3835(77)80024-4. Cancer Lett. 1977. PMID: 45722
-
Analysis of the transformation of human lymphocytes by Epstein-Barr virus III. Induction of early events by P3HR-1 strain without subsequent immortalization.Med Microbiol Immunol. 1981;170(1):19-26. doi: 10.1007/BF02123793. Med Microbiol Immunol. 1981. PMID: 6272076
-
Epstein-Barr virus nuclear antigen 2 induces expression of the virus-encoded latent membrane protein.J Virol. 1990 May;64(5):2126-34. doi: 10.1128/JVI.64.5.2126-2134.1990. J Virol. 1990. PMID: 2157875 Free PMC article.
-
Transfer of the Epstein-Barr virus (EBV) DNA fragment coding for EBNA-1, the putative transforming antigen of EBV, into normal human lymphocytes: gene expression without cell transformation.Biochem Biophys Res Commun. 1986 Feb 13;134(3):1260-8. doi: 10.1016/0006-291x(86)90386-4. Biochem Biophys Res Commun. 1986. PMID: 3004487
-
Retinoic acid and steroids inhibit Epstein-Barr virus-induced nuclear antigen, DNA synthesis and lymphocyte transformation.Anticancer Res. 1984 Nov-Dec;4(6):415-8. Anticancer Res. 1984. PMID: 6097161
Cited by
-
Nonresponsiveness to an immunodominant Epstein-Barr virus-encoded cytotoxic T-lymphocyte epitope in nuclear antigen 3A: implications for vaccine strategies.Proc Natl Acad Sci U S A. 1991 Nov 1;88(21):9478-82. doi: 10.1073/pnas.88.21.9478. Proc Natl Acad Sci U S A. 1991. PMID: 1719531 Free PMC article.
-
Host cell and EBNA-2 regulation of Epstein-Barr virus latent-cycle promoter activity in B lymphocytes.J Virol. 1992 Jan;66(1):496-504. doi: 10.1128/JVI.66.1.496-504.1992. J Virol. 1992. PMID: 1309259 Free PMC article.
-
Identification and characterization of an Epstein-Barr virus nuclear antigen 2-responsive cis element in the bidirectional promoter region of latent membrane protein and terminal protein 2 genes.J Virol. 1994 Nov;68(11):6947-58. doi: 10.1128/JVI.68.11.6947-6958.1994. J Virol. 1994. PMID: 7933076 Free PMC article.
-
Molecular basis for Epstein-Barr virus induced pathogenesis and disease.Springer Semin Immunopathol. 1991;13(2):133-46. doi: 10.1007/BF00201464. Springer Semin Immunopathol. 1991. PMID: 1664982 Review. No abstract available.
-
Delineation of the cis-acting element mediating EBNA-2 transactivation of latent infection membrane protein expression.J Virol. 1991 Dec;65(12):6765-71. doi: 10.1128/JVI.65.12.6765-6771.1991. J Virol. 1991. PMID: 1658373 Free PMC article.
References
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
