Cancer of the ovary, fallopian tube, and peritoneum
- PMID: 30306591
- DOI: 10.1002/ijgo.12614
Cancer of the ovary, fallopian tube, and peritoneum
Abstract
The Gynecologic Oncology Committee of FIGO in 2014 revised the staging of ovarian cancer, incorporating ovarian, fallopian tube, and peritoneal cancer into the same system. Most of these malignancies are high-grade serous carcinomas (HGSC). Stage IC is now divided into three categories: IC1 (surgical spill); IC2 (capsule ruptured before surgery or tumor on ovarian or fallopian tube surface); and IC3 (malignant cells in the ascites or peritoneal washings). The updated staging includes a revision of Stage IIIC based on spread to the retroperitoneal lymph nodes alone without intraperitoneal dissemination. This category is now subdivided into IIIA1(i) (metastasis ≤10 mm in greatest dimension), and IIIA1(ii) (metastasis >10 mm in greatest dimension). Stage IIIA2 is now "microscopic extrapelvic peritoneal involvement with or without positive retroperitoneal lymph node" metastasis. This review summarizes the genetics, surgical management, chemotherapy, and targeted therapies for epithelial cancers, and the treatment of ovarian germ cell and stromal malignancies.
Keywords: Cancer staging; Chemotherapy; FIGO Cancer Report; Fallopian tube; Ovarian; Ovary; Peritoneum.
© 2018 The Authors. International Journal of Gynecology & Obstetrics published by John Wiley & Sons Ltd on behalf of International Federation of Gynecology and Obstetrics.
Similar articles
-
Cancer of the ovary, fallopian tube, and peritoneum: 2021 update.Int J Gynaecol Obstet. 2021 Oct;155 Suppl 1(Suppl 1):61-85. doi: 10.1002/ijgo.13878. Int J Gynaecol Obstet. 2021. PMID: 34669199 Free PMC article. Review.
-
The new FIGO staging system for ovarian, fallopian tube, and primary peritoneal cancer.Arch Gynecol Obstet. 2014 Nov;290(5):839-42. doi: 10.1007/s00404-014-3364-8. Epub 2014 Aug 1. Arch Gynecol Obstet. 2014. PMID: 25082067
-
Ovarian, fallopian tube and peritoneal cancer staging: Rationale and explanation of new FIGO staging 2013.Best Pract Res Clin Obstet Gynaecol. 2015 Aug;29(6):858-69. doi: 10.1016/j.bpobgyn.2015.03.006. Epub 2015 Mar 31. Best Pract Res Clin Obstet Gynaecol. 2015. PMID: 25890882 Review.
-
Abridged republication of FIGO's staging classification for cancer of the ovary, fallopian tube, and peritoneum.Cancer. 2015 Oct 1;121(19):3452-4. doi: 10.1002/cncr.29524. Epub 2015 Jun 25. Cancer. 2015. PMID: 26110780
-
[New FIGO classification of ovarian, fallopian tube and primary peritoneal cancer].Pathologe. 2014 Jul;35(4):322-6. doi: 10.1007/s00292-014-1908-0. Pathologe. 2014. PMID: 24899496 German.
Cited by
-
Paradigm Shift: A Comprehensive Review of Ovarian Cancer Management in an Era of Advancements.Int J Mol Sci. 2024 Feb 3;25(3):1845. doi: 10.3390/ijms25031845. Int J Mol Sci. 2024. PMID: 38339123 Free PMC article. Review.
-
Intraoperative near-infrared fluorescence imaging can identify pelvic nerves in patients with cervical cancer in real time during radical hysterectomy.Eur J Nucl Med Mol Imaging. 2022 Jul;49(8):2929-2937. doi: 10.1007/s00259-022-05686-z. Epub 2022 Mar 1. Eur J Nucl Med Mol Imaging. 2022. PMID: 35230489 Free PMC article. Clinical Trial.
-
Current and Emerging Methods for Ovarian Cancer Screening and Diagnostics: A Comprehensive Review.Cancers (Basel). 2022 Jun 11;14(12):2885. doi: 10.3390/cancers14122885. Cancers (Basel). 2022. PMID: 35740550 Free PMC article. Review.
-
A New Paradigm in Managing Advanced Ovarian Cancer: Differentiating Patients Requiring Neoadjuvant Treatment from Primary Cytoreduction.Cancers (Basel). 2021 Sep 30;13(19):4925. doi: 10.3390/cancers13194925. Cancers (Basel). 2021. PMID: 34638409 Free PMC article.
-
The Role of Epithelial-to-Mesenchymal Plasticity in Ovarian Cancer Progression and Therapy Resistance.Cancers (Basel). 2019 Jun 17;11(6):838. doi: 10.3390/cancers11060838. Cancers (Basel). 2019. PMID: 31213009 Free PMC article. Review.
MeSH terms
LinkOut - more resources
Full Text Sources
Other Literature Sources
Medical
