Therapy of Skin, Hair and Nail Fungal Infections

doi:10.3390/jof4030099

Review

. 2018 Aug 20;4(3):99.

doi: 10.3390/jof4030099.

Therapy of Skin, Hair and Nail Fungal Infections

Roderick Hay¹

Affiliations

PMID: 30127244
PMCID: PMC6162762
DOI: 10.3390/jof4030099

Review

Therapy of Skin, Hair and Nail Fungal Infections

Roderick Hay. J Fungi (Basel). 2018.

. 2018 Aug 20;4(3):99.

doi: 10.3390/jof4030099.

Author

Roderick Hay¹

Affiliation

¹ Kings College London, London SE5 9RS, UK. roderick.hay@ifd.org.

PMID: 30127244
PMCID: PMC6162762
DOI: 10.3390/jof4030099

Abstract

Treatment of superficial fungal infections has come a long way. This has, in part, been through the development and evaluation of new drugs. However, utilising new strategies, such as identifying variation between different species in responsiveness, e.g., in tinea capitis, as well as seeking better ways of ensuring adequate concentrations of drug in the skin or nail, and combining different treatment methods, have played equally important roles in ensuring steady improvements in the results of treatment. Yet there are still areas where we look for improvement, such as better remission and cure rates in fungal nail disease, and the development of effective community treatment programmes to address endemic scalp ringworm.

Keywords: Malassezia infection; cutaneous candidiasis; dermatophytes; onychomycosis; treatment.

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Conflict of interest statement

The author declares no conflicts of interest.

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References

1. Gupta A.K., Sauder D.N., Shear N.H. Antifungal agents: An overview. Part I. J. Am. Acad. Dermatol. 1994;30:677–698. doi: 10.1016/S0190-9622(08)81495-8. - DOI - PubMed
1. Gupta A.K., Sauder D.N., Shear N.H. Antifungal agents: An overview. Part II. J. Am. Acad. Dermatol. 1994;30:911–933. doi: 10.1016/S0190-9622(94)70112-1. - DOI - PubMed
1. Crawford F., Hollis S. Topical treatments for fungal infections of the skin and nails of the foot. Cochrane Database Syst. Rev. 2007;3:CD001434. doi: 10.1002/14651858.CD001434.pub2. - DOI - PMC - PubMed
1. Rotta I., Ziegelmann P.K., Otuki M.F., Riveros B.S., Bernardo N.L., Correr C.J. Efficacy of topical antifungals in the treatment of dermatophytosis: A mixed-treatment comparison meta-analysis involving 14 treatments. JAMA Dermatol. 2013;149:341–349. doi: 10.1001/jamadermatol.2013.1721. - DOI - PubMed
1. Gupta A.K., Einarson T.R., Summerbell R.C., Shear N.H. An overview of topical antifungal therapy in dermatomycoses. A North American perspective. Drugs. 1998;55:645–674. doi: 10.2165/00003495-199855050-00004. - DOI - PubMed

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[1] Gupta A.K., Sauder D.N., Shear N.H. Antifungal agents: An overview. Part I. J. Am. Acad. Dermatol. 1994;30:677–698. doi: 10.1016/S0190-9622(08)81495-8. - DOI - PubMed

[2] Gupta A.K., Sauder D.N., Shear N.H. Antifungal agents: An overview. Part I. J. Am. Acad. Dermatol. 1994;30:677–698. doi: 10.1016/S0190-9622(08)81495-8. - DOI - PubMed

[3] Gupta A.K., Sauder D.N., Shear N.H. Antifungal agents: An overview. Part II. J. Am. Acad. Dermatol. 1994;30:911–933. doi: 10.1016/S0190-9622(94)70112-1. - DOI - PubMed

[4] Gupta A.K., Sauder D.N., Shear N.H. Antifungal agents: An overview. Part II. J. Am. Acad. Dermatol. 1994;30:911–933. doi: 10.1016/S0190-9622(94)70112-1. - DOI - PubMed

[5] Crawford F., Hollis S. Topical treatments for fungal infections of the skin and nails of the foot. Cochrane Database Syst. Rev. 2007;3:CD001434. doi: 10.1002/14651858.CD001434.pub2. - DOI - PMC - PubMed

[6] Crawford F., Hollis S. Topical treatments for fungal infections of the skin and nails of the foot. Cochrane Database Syst. Rev. 2007;3:CD001434. doi: 10.1002/14651858.CD001434.pub2. - DOI - PMC - PubMed

[7] Rotta I., Ziegelmann P.K., Otuki M.F., Riveros B.S., Bernardo N.L., Correr C.J. Efficacy of topical antifungals in the treatment of dermatophytosis: A mixed-treatment comparison meta-analysis involving 14 treatments. JAMA Dermatol. 2013;149:341–349. doi: 10.1001/jamadermatol.2013.1721. - DOI - PubMed

[8] Rotta I., Ziegelmann P.K., Otuki M.F., Riveros B.S., Bernardo N.L., Correr C.J. Efficacy of topical antifungals in the treatment of dermatophytosis: A mixed-treatment comparison meta-analysis involving 14 treatments. JAMA Dermatol. 2013;149:341–349. doi: 10.1001/jamadermatol.2013.1721. - DOI - PubMed

[9] Gupta A.K., Einarson T.R., Summerbell R.C., Shear N.H. An overview of topical antifungal therapy in dermatomycoses. A North American perspective. Drugs. 1998;55:645–674. doi: 10.2165/00003495-199855050-00004. - DOI - PubMed

[10] Gupta A.K., Einarson T.R., Summerbell R.C., Shear N.H. An overview of topical antifungal therapy in dermatomycoses. A North American perspective. Drugs. 1998;55:645–674. doi: 10.2165/00003495-199855050-00004. - DOI - PubMed

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Therapy of Skin, Hair and Nail Fungal Infections

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Therapy of Skin, Hair and Nail Fungal Infections

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