Latent herpes simplex virus type 1 DNA contains two copies of the virion DNA joint region
- PMID: 2991602
- PMCID: PMC255073
- DOI: 10.1128/JVI.55.3.849-852.1985
Latent herpes simplex virus type 1 DNA contains two copies of the virion DNA joint region
Abstract
Southern blot analysis of latent herpes simplex virus DNA detected in mouse brain and digested with a restriction enzyme revealed two copies of the virion DNA joint fragment. Thus, the absence of free ends noted previously in latent herpes simplex virus type 1 DNA is due to joining of the termini.
Similar articles
-
Latent herpes simplex virus type 1 transcripts in peripheral and central nervous system tissues of mice map to similar regions of the viral genome.J Virol. 1988 Mar;62(3):749-56. doi: 10.1128/JVI.62.3.749-756.1988. J Virol. 1988. PMID: 2828670 Free PMC article.
-
Latent herpes simplex virus type 1 DNA is not extensively methylated in vivo.J Gen Virol. 1987 Jun;68 ( Pt 6):1761-5. doi: 10.1099/0022-1317-68-6-1761. J Gen Virol. 1987. PMID: 3035069
-
Characterization of herpes simplex virus type 1 DNA during latent infection in mice.Pol Arch Weter. 1991;31(3-4):5-14. Pol Arch Weter. 1991. PMID: 1668805
-
Detection of herpes simplex virus-specific DNA sequences in latently infected mice and in humans.J Virol. 1986 Feb;57(2):446-55. doi: 10.1128/JVI.57.2.446-455.1986. J Virol. 1986. PMID: 3003377 Free PMC article.
-
Mechanisms of restriction of viral gene expression during herpes simplex virus latency.Adv Exp Med Biol. 1990;278:211-7. doi: 10.1007/978-1-4684-5853-4_22. Adv Exp Med Biol. 1990. PMID: 1963037 Review. No abstract available.
Cited by
-
A Journey through the Minefield of the Discovery and Characterization of Latency-Related RNA/Latency-Associated Transcript.Viruses. 2024 Sep 30;16(10):1562. doi: 10.3390/v16101562. Viruses. 2024. PMID: 39459896 Free PMC article. Review.
-
Latent herpes simplex virus type 1 transcripts in peripheral and central nervous system tissues of mice map to similar regions of the viral genome.J Virol. 1988 Mar;62(3):749-56. doi: 10.1128/JVI.62.3.749-756.1988. J Virol. 1988. PMID: 2828670 Free PMC article.
-
The herpes simplex virus type 1 latency-associated transcript (LAT) enhancer/rcr is hyperacetylated during latency independently of LAT transcription.J Virol. 2004 Nov;78(22):12508-18. doi: 10.1128/JVI.78.22.12508-12518.2004. J Virol. 2004. PMID: 15507638 Free PMC article.
-
In vivo changes in the patterns of chromatin structure associated with the latent herpes simplex virus type 1 genome in mouse trigeminal ganglia can be detected at early times after butyrate treatment.J Virol. 2007 Dec;81(23):13248-53. doi: 10.1128/JVI.01569-07. Epub 2007 Sep 19. J Virol. 2007. PMID: 17881451 Free PMC article.
-
Induction of herpes simplex virus type 1 immediate-early gene expression by a cellular activity expressed in Vero and NB41A3 cells after growth arrest-release.J Virol. 1994 Nov;68(11):6871-82. doi: 10.1128/JVI.68.11.6871-6882.1994. J Virol. 1994. PMID: 7933067 Free PMC article.
References
Publication types
MeSH terms
Substances
Grants and funding
LinkOut - more resources
Full Text Sources
Other Literature Sources