doi: 10.1084/jem.162.1.363.
Stable expression of cDNA encoding the human interleukin 2 receptor in eukaryotic cells
- PMID: 2989411
- PMCID: PMC2187706
- DOI: 10.1084/jem.162.1.363
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Stable expression of cDNA encoding the human interleukin 2 receptor in eukaryotic cells
J Exp Med.
.
Abstract
Human interleukin 2 (IL-2) receptor cDNA derived from HUT 102B2 cells was stably expressed in murine L cells. These L cell transfectants (a) displayed surface receptors of the aberrant size of the IL-2 receptors on HUT 102B2 cells, (b) did not respond to exogenous IL-2 with augmented proliferation, and (c) expressed low affinity but not high affinity receptors for IL-2.
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