doi: 10.2337/diab.34.2.197.
Administration of silica prevents diabetes in BB-rats
- PMID: 2981751
- DOI: 10.2337/diab.34.2.197
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Administration of silica prevents diabetes in BB-rats
Diabetes.
1985 Feb.
Abstract
Administration of silica to young BB-rats almost completely prevented the development of spontaneous diabetes. Only 1 of 31 silica-treated rats developed hyperglycemia, whereas 9 of 31 in the untreated group did so. Since silica is highly specific in its action against macrophages, our observations indicate an important role of these cells in the pathogenesis of the disease.
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