Haploinsufficiency of A20 causes autoinflammatory and autoimmune disorders

doi:10.1016/j.jaci.2017.10.039

Multicenter Study

. 2018 Apr;141(4):1485-1488.e11.

doi: 10.1016/j.jaci.2017.10.039. Epub 2017 Dec 11.

Haploinsufficiency of A20 causes autoinflammatory and autoimmune disorders

Tomonori Kadowaki¹, Hidenori Ohnishi¹, Norio Kawamoto¹, Tomohiro Hori¹, Kenichi Nishimura², Chie Kobayashi³, Tomonari Shigemura⁴, Shohei Ogata⁵, Yuzaburo Inoue⁶, Tomoki Kawai⁷, Eitaro Hiejima⁷, Masatoshi Takagi⁸, Kohsuke Imai⁸, Ryuta Nishikomori⁷, Shuichi Ito², Toshio Heike⁷, Osamu Ohara⁹, Tomohiro Morio¹⁰, Toshiyuki Fukao¹¹, Hirokazu Kanegane¹²

Affiliations

¹ Department of Pediatrics, Gifu University Graduate School of Medicine, Gifu, Japan.
² Department of Pediatrics, Yokohama City University, Yokohama, Kanagawa, Japan.
³ Department of Child Health, Faculty of Medicine, University of Tsukuba, Tsukuba, Ibaraki, Japan.
⁴ Department of Pediatrics, Shinshu University School of Medicine, Matsumoto, Japan.
⁵ Department of Pediatrics, Kitasato University Hospital, Sagamihara, Kanagawa, Japan.
⁶ Department of Pediatrics, Eastern Chiba Medical Center, Chiba, Japan.
⁷ Department of Pediatrics, Kyoto University Hospital, Kyoto, Japan.
⁸ Department of Community Pediatrics, Perinatal and Maternal Medicine Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo, Japan.
⁹ Department of Technology Development, Kazusa DNA Research Institute, Chiba, Japan.
¹⁰ Department of Pediatrics and Developmental Biology, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo, Japan.
¹¹ Department of Pediatrics, Gifu University Graduate School of Medicine, Gifu, Japan. Electronic address: toshi-gif@umin.net.
¹² Department of Pediatrics and Developmental Biology, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo, Japan. Electronic address: hkanegane.ped@tmd.ac.jp.

PMID: 29241730
DOI: 10.1016/j.jaci.2017.10.039

Multicenter Study

Haploinsufficiency of A20 causes autoinflammatory and autoimmune disorders

Tomonori Kadowaki et al. J Allergy Clin Immunol. 2018 Apr.

. 2018 Apr;141(4):1485-1488.e11.

doi: 10.1016/j.jaci.2017.10.039. Epub 2017 Dec 11.

Authors

Affiliations

¹ Department of Pediatrics, Gifu University Graduate School of Medicine, Gifu, Japan.
² Department of Pediatrics, Yokohama City University, Yokohama, Kanagawa, Japan.
³ Department of Child Health, Faculty of Medicine, University of Tsukuba, Tsukuba, Ibaraki, Japan.
⁴ Department of Pediatrics, Shinshu University School of Medicine, Matsumoto, Japan.
⁵ Department of Pediatrics, Kitasato University Hospital, Sagamihara, Kanagawa, Japan.
⁶ Department of Pediatrics, Eastern Chiba Medical Center, Chiba, Japan.
⁷ Department of Pediatrics, Kyoto University Hospital, Kyoto, Japan.
⁸ Department of Community Pediatrics, Perinatal and Maternal Medicine Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo, Japan.
⁹ Department of Technology Development, Kazusa DNA Research Institute, Chiba, Japan.
¹⁰ Department of Pediatrics and Developmental Biology, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo, Japan.
¹¹ Department of Pediatrics, Gifu University Graduate School of Medicine, Gifu, Japan. Electronic address: toshi-gif@umin.net.
¹² Department of Pediatrics and Developmental Biology, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo, Japan. Electronic address: hkanegane.ped@tmd.ac.jp.

PMID: 29241730
DOI: 10.1016/j.jaci.2017.10.039

No abstract available

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Haploinsufficiency of A20 causes autoinflammatory and autoimmune disorders

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