Human spermatogonial markers
- PMID: 29239848
- DOI: 10.1016/j.scr.2017.11.011
Human spermatogonial markers
Abstract
In this review, we provide an up-to-date compilation of published human spermatogonial markers, with focus on the three nuclear subtypes Adark, Apale and B. In addition, we have extended our recently published list of putative spermatogonial markers with protein expression and RNA-sequencing data from the Human Protein Atlas and supported these by literature evidence. Most importantly, we have put substantial effort in acquiring a comprehensive list of new and potentially interesting markers by refiltering the raw data of 15 published germ cell expression datasets (four human, eleven rodent) and subsequent building of intersections to acquire a robust, cross-species set of spermatogonia-enriched or -specific transcripts.
Keywords: Gene expression; Microarray; RNA sequencing; Spermatogonia; Stem cells.
Copyright © 2017 The Authors. Published by Elsevier B.V. All rights reserved.
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