Review
doi: 10.1007/978-94-024-1088-4_3.
TRPC Channel Downstream Signaling Cascades
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- PMID: 28508310
- DOI: 10.1007/978-94-024-1088-4_3
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Review
TRPC Channel Downstream Signaling Cascades
Adv Exp Med Biol.
2017.
Abstract
The family of TRP channel is comprised of a large group of cation-permeable channels, displaying as signaling integrators for sensing extracellular stimulus and initiating intracellular signaling cascades. This chapter offers a brief review of the signaling molecules related to TRPC channels, the first identified mammalian TRP family. Besides the signaling molecules involved in TRPC activation, I will focus on their upstream and downstream signaling cascades and the molecules involved in their intracellular trafficking.
Keywords: Intracellular trafficking; Signaling cascades; TRPC.
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