Review
doi: 10.1016/j.chom.2017.02.003.
Trained Immunity: An Ancient Way of Remembering
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- PMID: 28279335
- DOI: 10.1016/j.chom.2017.02.003
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Review
Trained Immunity: An Ancient Way of Remembering
Cell Host Microbe.
.
Free article
Abstract
The innate arm of the immune system has generally been regarded as primitive and non-specific and, in contrast to adaptive immunity, not to possess memory. Here we review the growing body of evidence that innate immunity has an important capacity to adapt, a de facto innate immune memory (also termed trained immunity), and this provides broad protection against infections.
Keywords: cytokines; infections; innate immune memory; trained immunity; vertebrate immunity.
Copyright © 2017 Elsevier Inc. All rights reserved.
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