doi: 10.1128/mcb.8.1.461-465.1988.
Phosphorylation of p53 in normal and simian virus 40-transformed NIH 3T3 cells
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- PMID: 2827007
- PMCID: PMC363151
- DOI: 10.1128/mcb.8.1.461-465.1988
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Phosphorylation of p53 in normal and simian virus 40-transformed NIH 3T3 cells
Mol Cell Biol.
1988 Jan.
Abstract
We observed six major tryptic phosphopeptides in p53 from simian virus 40-transformed and normal NIH 3T3 cells. Analyses of the phosphopeptides indicated that serines 37, 310 and/or 312, 389 and one or more of serines 7, 9, 12, 18, and 23 were phosphorylated. Phosphorylation of serines 310 and/or 312 was twofold higher in the simian virus 40-transformed cells as compared with that in normal NIH 3T3 cells.
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