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Review
. 2016 Oct;70(5):331-337.
doi: 10.18926/AMO/54590.

The Clinical Application of Hydrogen as a Medical Treatment

Atsuyoshi Iida  1 , Nobuyuki Nosaka, Tetsuya Yumoto, Emily Knaup, Hiromichi Naito, Chihiro Nishiyama, Yasuaki Yamakawa, Kohei Tsukahara, Michihisa Terado, Keiji Sato, Toyomu Ugawa, Atsunori Nakao
Affiliations
Free article
Review

The Clinical Application of Hydrogen as a Medical Treatment

Atsuyoshi Iida et al. Acta Med Okayama. 2016 Oct.
Free article

Abstract

In recent years, it has become evident that molecular hydrogen is a particularyl effective treatment for various disease models such as ischemia-reperfusion injury; as a result, research on hydrogen has progressed rapidly. Hydrogen has been shown to be effective not only through intake as a gas, but also as a liquid medication taken orally, intravenously, or locally. Hydrogen's effectiveness is thus multifaceted. Herein we review the recent research on hydrogen-rich water, and we examine the possibilities for its clinical application. Now that hydrogen is in the limelight as a gaseous signaling molecule due to its potential ability to inhibit oxidative stress signaling, new research developments are highly anticipated.

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