Contrast-Induced Acute Kidney Injury

doi:10.1016/j.jacc.2016.05.099

Review

. 2016 Sep 27;68(13):1465-1473.

doi: 10.1016/j.jacc.2016.05.099.

Contrast-Induced Acute Kidney Injury

Peter A McCullough¹, James P Choi², Georges A Feghali², Jeffrey M Schussler², Robert M Stoler², Ravi C Vallabahn², Ankit Mehta³

Affiliations

¹ Department of Internal Medicine, Division of Cardiology, Baylor University Medical Center, Dallas, Texas; Baylor Heart and Vascular Institute, Dallas, Texas; Baylor Jack and Jane Hamilton Heart and Vascular Hospital, Dallas, Texas; The Heart Hospital Baylor Plano, Plano, Texas. Electronic address: peteramccullough@gmail.com.
² Baylor Jack and Jane Hamilton Heart and Vascular Hospital, Dallas, Texas.
³ Department of Internal Medicine, Division of Cardiology, Baylor University Medical Center, Dallas, Texas.

PMID: 27659469
DOI: 10.1016/j.jacc.2016.05.099

Free article

Review

Contrast-Induced Acute Kidney Injury

Peter A McCullough et al. J Am Coll Cardiol. 2016.

Free article

. 2016 Sep 27;68(13):1465-1473.

doi: 10.1016/j.jacc.2016.05.099.

Authors

Peter A McCullough¹, James P Choi², Georges A Feghali², Jeffrey M Schussler², Robert M Stoler², Ravi C Vallabahn², Ankit Mehta³

Affiliations

¹ Department of Internal Medicine, Division of Cardiology, Baylor University Medical Center, Dallas, Texas; Baylor Heart and Vascular Institute, Dallas, Texas; Baylor Jack and Jane Hamilton Heart and Vascular Hospital, Dallas, Texas; The Heart Hospital Baylor Plano, Plano, Texas. Electronic address: peteramccullough@gmail.com.
² Baylor Jack and Jane Hamilton Heart and Vascular Hospital, Dallas, Texas.
³ Department of Internal Medicine, Division of Cardiology, Baylor University Medical Center, Dallas, Texas.

PMID: 27659469
DOI: 10.1016/j.jacc.2016.05.099

Abstract

Coronary angiography and percutaneous intervention rely on the use of iodinated intravascular contrast for vessel and chamber imaging. Despite advancements in imaging and interventional techniques, iodinated contrast continues to pose a risk of contrast-induced acute kidney injury (CI-AKI) for a subgroup of patients at risk for this complication. There has been a consistent and graded signal of risk for associated outcomes including need for renal replacement therapy, rehospitalization, and death, according to the incidence and severity of CI-AKI. This paper reviews the epidemiology, pathophysiology, prognosis, and management of CI-AKI as it applies to the cardiac catheterization laboratory.

Keywords: cardiac catheterization; coronary angiography; iodine; percutaneous coronary intervention.

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Comment in

Reply: Vitamin E May Protect Against Contrast-Induced Acute Kidney Injury.
McCullough PA. McCullough PA. J Am Coll Cardiol. 2017 Apr 11;69(14):1878-1879. doi: 10.1016/j.jacc.2017.01.053. J Am Coll Cardiol. 2017. PMID: 28385321 No abstract available.
Vitamin E May Protect Against Contrast-Induced Acute Kidney Injury.
Hemilä H, Rezaei Y. Hemilä H, et al. J Am Coll Cardiol. 2017 Apr 11;69(14):1878. doi: 10.1016/j.jacc.2016.11.091. J Am Coll Cardiol. 2017. PMID: 28385322 No abstract available.

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Contrast-Induced Acute Kidney Injury

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