Investigational nanomedicines in 2016: a review of nanotherapeutics currently undergoing clinical trials
- PMID: 27312983
- DOI: 10.1002/wnan.1416
Investigational nanomedicines in 2016: a review of nanotherapeutics currently undergoing clinical trials
Abstract
Nanomedicine is a relatively new field that is rapidly evolving. Formulation of drugs on the nanoscale imparts many physical and biological advantages. Such advantages can in turn translate into improved therapeutic efficacy and reduced toxicity. While approximately 50 nanotherapeutics have already entered clinical practice, a greater number of drugs are undergoing clinical investigation for a variety of indications. This review aims to examine all the nanoformulations that are currently undergoing clinical investigation and their outlook for ultimate clinical translation. WIREs Nanomed Nanobiotechnol 2017, 9:e1416. doi: 10.1002/wnan.1416 For further resources related to this article, please visit the WIREs website.
© 2016 Wiley Periodicals, Inc.
Similar articles
-
Nanomedicine approaches to improve cancer immunotherapy.Wiley Interdiscip Rev Nanomed Nanobiotechnol. 2017 Sep;9(5):10.1002/wnan.1456. doi: 10.1002/wnan.1456. Epub 2017 Mar 10. Wiley Interdiscip Rev Nanomed Nanobiotechnol. 2017. PMID: 28296286 Free PMC article. Review.
-
Challenges in preclinical to clinical translation for anticancer carrier-mediated agents.Wiley Interdiscip Rev Nanomed Nanobiotechnol. 2016 Sep;8(5):642-53. doi: 10.1002/wnan.1394. Epub 2016 Feb 5. Wiley Interdiscip Rev Nanomed Nanobiotechnol. 2016. PMID: 26846457 Review.
-
Tumor-targeted nanotherapeutics: overcoming treatment barriers for glioblastoma.Wiley Interdiscip Rev Nanomed Nanobiotechnol. 2017 Jul;9(4):10.1002/wnan.1439. doi: 10.1002/wnan.1439. Epub 2016 Nov 4. Wiley Interdiscip Rev Nanomed Nanobiotechnol. 2017. PMID: 27813323 Free PMC article. Review.
-
Viral chemistry: the chemical functionalization of viral architectures to create new technology.Wiley Interdiscip Rev Nanomed Nanobiotechnol. 2016 Jul;8(4):512-34. doi: 10.1002/wnan.1379. Epub 2015 Dec 10. Wiley Interdiscip Rev Nanomed Nanobiotechnol. 2016. PMID: 26663821 Review.
-
Peptide nanostructures in biomedical technology.Wiley Interdiscip Rev Nanomed Nanobiotechnol. 2016 Sep;8(5):730-43. doi: 10.1002/wnan.1393. Epub 2016 Feb 5. Wiley Interdiscip Rev Nanomed Nanobiotechnol. 2016. PMID: 26846352 Review.
Cited by
-
Nanomedicines as a cutting-edge solution to combat antimicrobial resistance.RSC Adv. 2024 Oct 22;14(45):33568-33586. doi: 10.1039/d4ra06117a. eCollection 2024 Oct 17. RSC Adv. 2024. PMID: 39439838 Free PMC article. Review.
-
Nanocarriers for targeted drug delivery in the vascular system: focus on endothelium.J Nanobiotechnology. 2024 Oct 12;22(1):620. doi: 10.1186/s12951-024-02892-9. J Nanobiotechnology. 2024. PMID: 39396002 Free PMC article. Review.
-
Realizing active targeting in cancer nanomedicine with ultrasmall nanoparticles.Beilstein J Nanotechnol. 2024 Sep 30;15:1208-1226. doi: 10.3762/bjnano.15.98. eCollection 2024. Beilstein J Nanotechnol. 2024. PMID: 39376728 Free PMC article. Review.
-
Lymphoid organ-targeted nanomaterials for immunomodulation of cancer, inflammation, and beyond.Chem Soc Rev. 2024 Jul 29;53(15):7657-7680. doi: 10.1039/d4cs00421c. Chem Soc Rev. 2024. PMID: 38958009 Review.
-
Development of solid lipid nanoparticles-loaded drugs in parasitic diseases.Discov Nano. 2024 Jan 4;19(1):7. doi: 10.1186/s11671-023-03955-w. Discov Nano. 2024. PMID: 38175309 Free PMC article. Review.
Publication types
MeSH terms
Substances
Grants and funding
LinkOut - more resources
Full Text Sources
Other Literature Sources
Medical
