doi: 10.1002/cpt.376.
Epub 2016 May 9.
Maternal use of selective serotonin-reuptake inhibitors and risk of persistent pulmonary hypertension of the newborn
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- PMID: 27060574
- DOI: 10.1002/cpt.376
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Maternal use of selective serotonin-reuptake inhibitors and risk of persistent pulmonary hypertension of the newborn
Clin Pharmacol Ther.
2016 Jul.
Abstract
Use of selective serotonin reuptake inhibitors (SSRIs) in late pregnancy has been associated with persistent pulmonary hypertension of the newborn (PPHN), a rare condition with substantial infant mortality and morbidity. Although the increase in absolute risk is small on a population level, it may be of concern to many patients. It remains unclear the extent to which the increased risks reported for PPHN are explained by the underlying maternal illness rather than the use of SSRIs.
© 2016 American Society for Clinical Pharmacology and Therapeutics.
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